Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18216985 | 0.89 | SLC2A1 (0.46) | ADRA2AALDH1A1TSHRALOX15HSD17B10 | |
| SCHEMBL6152657 | 0.82 | MAPT (0.50) | ALDH1A1MAPTGAARAB9AMAPK1 | |
| SCHEMBL13159580 | 0.81 | MAPT (0.54) | ADRA2AALDH1A1TSHRALOX15HSD17B10 | |
| SCHEMBL10668913 | 0.80 | MAPT (0.53) | ALDH1A1TSHRMAPTGAASMN1; SMN2 | |
| SCHEMBL6571406 | 0.79 | ADRA2A (0.40) | ADRA2AALDH1A1ALOX15HSD17B10MAPT | |
| SCHEMBL11507189 | 0.79 | MAPT (0.55) | ALDH1A1MAPTGAARAB9AMAPK1 | |
| SCHEMBL4171220 | 0.79 | ALDH1A1 (0.46) | ALDH1A1TSHRALOX15HSD17B10MAPT | |
| SCHEMBL20837983 | 0.79 | HDAC1 (0.46) | ALDH1A1TSHRALOX15HSD17B10MAPT | |
| SCHEMBL10848850 | 0.79 | CA1 (0.46) | ADRA2AALDH1A1TSHRALOX15HSD17B10 | |
| Hydrochloric Acid SCHEMBL9660653 | 0.79 | MAPT (0.51) | ALDH1A1TSHRMAPTGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090023735-A1 | Sulphonamide Derivatives | BIOTIE THERAPIES CORP. (FI) | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023735-A1 | Sulphonamide Derivatives | HCAR1, ADGRE5, ALK | ADRA2A 375/4885ALDH1A1 872/4885TSHR 648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.