Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1822048 | 1.00 | MAP3K14 (0.45) | MAP3K14PAK4 | |
| SCHEMBL1614185 | 0.96 | MAP3K14 (0.49) | MAP3K14PAK4 | |
| SCHEMBL1613528 | 0.88 | PAK4 (0.49) | MAP3K14PAK4 | |
| SCHEMBL12743916 | 0.86 | ERBB2 (0.35) | MAP3K14 | |
| SCHEMBL1822232 | 0.84 | MAP3K14 (0.64) | MAP3K14 | |
| SCHEMBL1614900 | 0.84 | MAP3K14 (0.64) | MAP3K14 | |
| SCHEMBL1614897 | 0.84 | MAP3K14 (0.64) | MAP3K14 | |
| SCHEMBL1611642 | 0.82 | MAP3K14 (0.50) | MAP3K14PAK4 | |
| SCHEMBL1613979 | 0.82 | PAK4 (0.46) | MAP3K14PAK4 | |
| SCHEMBL1613974 | 0.82 | PAK4 (0.46) | MAP3K14PAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2315751-A1 | ALKYNYL ALCOHOLS AS KINASE INHIBITORS | Amgen Inc. (US) | 2011-05-04 | — | — | EP | disclosed |
| WO-2009158011-A1 | ALKYNYL ALCOHOLS AS KINASE INHIBITORS | AMGEN INC. (US) | 2009-12-30 | — | — | WO | disclosed |