Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17530030 | 0.94 | ACE (0.51) | ACECYP2D6ALDH1A1CA1KMT2A | |
| SCHEMBL9518399 | 0.84 | CYP2D6 (0.49) | ACECYP2D6ALDH1A1CA1CA2 | |
| SCHEMBL14809033 | 0.83 | CYP2D6 (0.44) | ACECYP2D6ALDH1A1CA1CA2 | |
| SCHEMBL11639674 | 0.82 | CYP2D6 (0.48) | ACECYP2D6ALDH1A1CA1CA2 | |
| SCHEMBL11091265 | 0.80 | CYP2D6 (0.44) | ACECYP2D6ALDH1A1CA1CA2 | |
| SCHEMBL2037723 | 0.79 | CYP2D6 (0.41) | ACECYP2D6ALDH1A1CA1CA2 | |
| SCHEMBL6287504 | 0.78 | CYP2D6 (0.43) | ACECYP2D6ALDH1A1CA1CA2 | |
| SCHEMBL2042009 | 0.78 | CYP2D6 (0.40) | ACECYP2D6ALDH1A1CA1CA2 | |
| SCHEMBL2042008 | 0.78 | CYP2D6 (0.40) | ACECYP2D6ALDH1A1CA1CA2 | |
| SCHEMBL2728837 | 0.78 | THRB (0.46) | ACECYP2D6ALDH1A1POLBUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114423822-A | Polyamide composition | 巴斯夫欧洲公司 | 2022-04-29 | — | — | CN | disclosed |
| US-20170158637-A1 | Synthetic Processes of Carprofen | CHEMWERTH, INC. | 2017-06-08 | — | — | US | disclosed |
| CN-106244044-A | A kind of seccotine | 无锡万能胶粘剂有限公司 | 2016-12-21 | — | — | CN | disclosed |
| US-20160326113-A1 | Synthetic Processes of Carprofen | CHEMWERTH, INC. | 2016-11-10 | — | — | US | disclosed |
| CN-1246512-C | Process for making yarns, fibers and filaments | RHODIA POLYAMIDE INTERMEDIATES (FR) | 2006-03-22 | — | — | CN | disclosed |
| CN-1492953-A | Method for making yarn fibres and filaments | ���Ǿ������м��幫˾ | 2004-04-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160326113-A1 | Synthetic Processes of Carprofen | CYP4F2, CYP4F3, CYP2J2 | ACE 1376/4885CYP2D6 26/4885ALDH1A1 766/4885 |
| US-20170158637-A1 | Synthetic Processes of Carprofen | CYP4F2, CYP4F3, CYP2J2 | ACE 1376/4885CYP2D6 26/4885ALDH1A1 766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.