SCHEMBL1822141

SCHEMBL1822141

NCCCC(N)(c1ccc(N)cc1)c1ccc(N)cc1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 11/20 0.43
LOXL2 Q9Y4K0 1/20 0.37
KCNH2 Q12809 2/20 0.37
MAPT P10636 3/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
TAAR1 Q96RJ0 1/20 0.34
NPC1 O15118 2/20 0.33
ALDH1A1 P00352 2/20 0.33
RAB9A P51151 2/20 0.33
CYP3A4 P08684 2/20 0.33
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33
GFER P55789 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3630705 0.79 KIF11 (0.68) KIF11KCNH2TAAR1CYP3A4CYP2D6
SCHEMBL1463293 0.75 MAPT (0.44) KIF11LOXL2MAPTMEN1KMT2A
SCHEMBL459552 0.75 KIF11 (0.41) KIF11KCNH2CYP3A4CYP2D6CYP2C9
SCHEMBL11323347 0.74 MAPT (0.42) KIF11MAPTMEN1KMT2ANPC1
SCHEMBL28472455 0.73 KIF11 (0.59) KIF11KCNH2TAAR1CYP3A4CYP2D6
SCHEMBL28158246 0.72 CA12 (0.53) LOXL2MAPTMEN1KMT2AALDH1A1
SCHEMBL11123599 0.72 CA12 (0.53) LOXL2MAPTMEN1KMT2AALDH1A1
SCHEMBL459124 0.71 KIF11 (0.40) KIF11LOXL2MAPTMEN1KMT2A
SCHEMBL902585 0.71 KIF11 (0.57) KIF11KCNH2TAAR1CYP3A4CYP2D6
SCHEMBL29674396 0.71 KIF11 (0.57) KIF11KCNH2TAAR1CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1047376-B2 KERATINOUS FIBRE DYEING COMPOSITION CONTAINING A LACCASE AND DYEING METHOD USING SAME OREAL (FR) 2009-03-18 EP claimed
US-6702863-B1 SINGLE PACKAGE AEROSOL CONPRISED OF 5,6-DIHYDROXYINDOLINE, LACCASE, WATER AND PROPELLANT; NONIRRITATING; STORAGE STABLE LION CORPORATION (JP) 2004-03-09 US claimed
EP-1367983-A1 MICROCAPSULES WITH AQUEOUS CORE CONTAINING OXIDATION-REDUCTION ENZYMES AND THEIR USE IN OXIDATION DYEING COMPOSITIONS L'OREAL (FR) 2003-12-10 EP claimed
EP-1326578-A1 OXIDATION COLORANTS COMPRISING 2-CHLORO-P-AMINOPHENOL Henkel Kommanditgesellschaft auf Aktien (DE) 2003-07-16 EP claimed
EP-1292272-A2 OXIDISED HAIR DYE Henkel Kommanditgesellschaft auf Aktien (DE) 2003-03-19 EP claimed
WO-2002069922-A1 MICROCAPSULES WITH AQUEOUS CORE CONTAINING OXIDATION-REDUCTION ENZYMES AND THEIR USE IN OXIDATION DYEING COMPOSITIONS L'OREAL (FR) 2002-09-12 WO claimed
EP-1235550-A2 NEW COLOURING COMBINATION Henkel Kommanditgesellschaft auf Aktien (DE) 2002-09-04 EP claimed
WO-2002032385-A1 OXIDATION COLORANTS COMPRISING 2-CHLORO-P-AMINOPHENOL HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-04-25 WO claimed
WO-2001097766-A2 OXIDISED HAIR DYE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-12-27 WO claimed
WO-2001041717-A2 NEW COLOURING COMBINATION HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-06-14 WO claimed
CN-120035427-A Composition for lightening keratin fibres and method for lightening keratin fibres using said composition 莱雅公司 2025-05-23 CN disclosed
CN-119968189-A Composition for lightening keratin fibres and method for lightening keratin fibres using said composition 莱雅公司 2025-05-09 CN disclosed
CN-119894486-A Composition for lightening keratin fibres and method for lightening keratin fibres using said composition 莱雅公司 2025-04-25 CN disclosed
CN-119855579-A Composition for lightening keratin fibres and method for lightening keratin fibres using said composition 莱雅公司 2025-04-18 CN disclosed
CN-119836282-A Composition for lightening keratin fibres and method for lightening keratin fibres using said composition 莱雅公司 2025-04-15 CN disclosed
EP-0424261-B1 Dyeing composition containing oxidation dyes precursors and aminoindole derivatives as coupling agent OREAL (FR) 1996-01-03 EP disclosed
EP-0428442-B1 Composition comprising derivatives of 6- or 7-hydroxyindole as couplers and dyeing processes using same OREAL (FR) 1994-08-31 EP disclosed
EP-0428441-A2 Keratinic fibre dyeing compostions containing oxydation dye precursors and derivatives of 4-hydroxyindole as couplers, and dyeing process using same L'OREAL (FR) 1991-05-22 EP disclosed
EP-0428442-A1 Composition comprising derivatives of 6- or 7-hydroxyindole as couplers and dyeing processes using same L'OREAL (FR) 1991-05-22 EP disclosed
EP-0424261-A1 Dyeing composition containing oxidation dyes precursors and aminoindole derivatives as coupling agent L'OREAL (FR) 1991-04-24 EP disclosed