SCHEMBL1463293

SCHEMBL1463293

NCC(N)(c1ccc(N)cc1)c1ccc(N)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
LOXL2 Q9Y4K0 1/20 0.43
KIF11 P52732 1/20 0.42
ALDH1A1 P00352 6/20 0.39
CYP3A4 P08684 4/20 0.39
TDP1 Q9NUW8 3/20 0.39
TSHR P16473 2/20 0.39
GFER P55789 1/20 0.39
TP53 P04637 1/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
MAPK1 P28482 2/20 0.38
HPGD P15428 1/20 0.38
MAOB P27338 3/20 0.35
ALOX15 P16050 2/20 0.35
ACHE P22303 1/20 0.35
CA3 P07451 1/20 0.35
THRB P10828 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3264276 0.76 HTR2A (0.42) ALDH1A1MAPK1MAOBALOX15TAAR1
SCHEMBL15558948 0.76 TAAR1 (0.54) KIF11ALDH1A1TSHRMAOBTAAR1
SCHEMBL6060758 0.76 TSHR (0.48) MAPTKIF11TDP1TSHRNPC1
SCHEMBL4459928 0.76 LOXL2 (0.46) LOXL2KIF11CYP3A4RAB9AMAOB
SCHEMBL4976900 0.76 TSHR (0.46) MAPTMEN1KMT2AKIF11ALDH1A1
SCHEMBL6641361 0.76 ESR1 (0.46) MAPTMEN1KMT2AKIF11ALDH1A1
SCHEMBL9456971 0.76 MAPT (0.57) MAPTMEN1KMT2ALOXL2KIF11
SCHEMBL1822141 0.75 KIF11 (0.43) MAPTMEN1KMT2ALOXL2KIF11
SCHEMBL150158 0.74 TAAR1 (0.56) LOXL2KIF11ALDH1A1TSHRTAAR1
SCHEMBL10574062 0.74 TAAR1 (0.62) MAPTMEN1KMT2ALOXL2KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105637410-B Liquid crystal display element 日产化学工业株式会社 2019-08-02 CN disclosed
CN-105593752-B Liquid crystal indicates element, aligning agent for liquid crystal and liquid crystal orientation film 日产化学工业株式会社 2019-01-22 CN disclosed
CN-106459500-B Rubber composition, tire, bis-phenylenediamine compound, and aging inhibitor 大塚化学株式会社 2018-08-03 CN disclosed
WO-2017109182-A1 COMPOSITION COMPRISING AT LEAST TWO DIFFERENT STARCHES AND A COLOURING AGENT L'OREAL (FR) 2017-06-29 WO disclosed
CN-106459500-A Rubber composition, tire, bis-phenylenediamine compound, and aging inhibitor 大塚化学株式会社 2017-02-22 CN disclosed
EP-3086860-A1 OXIDATION DYEING PROCESS USING A SUBSTRATE BEARING AT LEAST ONE OXIDATION DYE AND AN AQUEOUS COMPOSITION L'Oréal (FR) 2016-11-02 EP disclosed
EP-2903585-A2 AGENT FOR ALTERING THE COLOR OF KERATIN FIBERS COMPRISING A FATTY SUBSTANCE, A RHEOLOGY MODIFYING POLYMER, AND DIRECT DYES IN AN EMULSION SYSTEM L'OREAL (FR) 2015-08-12 EP disclosed
EP-2903584-A2 AGENT FOR ALTERING THE COLOR OF KERATIN FIBERS CONTAINING A FATTY SUBSTANCE AND A RHEOLOGY MODIFYING POLYMER IN AN EMULSION SYSTEM L'OREAL (FR) 2015-08-12 EP disclosed
WO-2015097307-A1 OXIDATION DYEING PROCESS USING A SUBSTRATE BEARING AT LEAST ONE OXIDATION DYE AND AN AQUEOUS COMPOSITION L'OREAL (FR) 2015-07-02 WO disclosed
WO-2015063124-A1 DYEING METHOD EMPLOYING AN EXPANDED OXIDIZING COMPOSITION L'OREAL (FR) 2015-05-07 WO disclosed
US-20030106166-A1 Compositions for dyeing keratinous fiber LION CORPORATION (JP) 2003-06-12 US disclosed
EP-1317243-A1 HAIR DYEING AGENTS CONTAINING INDIGO DERIVATIVES Henkel Kommanditgesellschaft auf Aktien (DE) 2003-06-11 EP disclosed
EP-1286646-A1 OXIDATION DYEING METHOD FOR KERATINOUS FIBERS Henkel Kommanditgesellschaft auf Aktien (DE) 2003-03-05 EP disclosed
WO-2002087515-A2 ACTIVE INGREDIENT COMBINATIONS FOR HAIR-DYEING AGENTS HANS SCHWARZKOPF & HENKEL GMBH & CO. KG (DE) 2002-11-07 WO disclosed
EP-1234569-A1 COMPOSITIONS FOR DYEING HORNY FIBERS Lion Corporation (JP) 2002-08-28 EP disclosed
WO-2002032379-A2 OXIDATION COLORANTS CONTAINING 2-CHLORO-4-AMINOPHENOL HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-04-25 WO disclosed
WO-2002022092-A1 HAIR DYEING AGENTS CONTAINING INDIGO DERIVATIVES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-03-21 WO disclosed
WO-2001093819-A1 OXIDATION DYEING METHOD FOR KERATINOUS FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-12-13 WO disclosed
EP-1137391-A1 METHOD FOR TREATING HAIR Novozymes A/S (DK) 2001-10-04 EP disclosed
WO-2000032158-A1 METHOD FOR TREATING HAIR NOVOZYMES A/S (DK) 2000-06-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030106166-A1 Compositions for dyeing keratinous fiber KRT18, LPO, CKMT1A; CKMT1B MAPT 1133/4885MEN1 4849/4885KMT2A 1436/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.