SCHEMBL1822149

SCHEMBL1822149

CCCCCC([Si](CC)(CC)OCC)[Si](CC)(CC)OCC

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.39
FDPS P14324 4/20 0.34
TP53 P04637 1/20 0.32
LMNA P02545 1/20 0.32
DNM1 Q05193 2/20 0.31
SMPD1 P17405 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1821835 0.85 FDPS (0.33) OPRM1FDPSLMNADNM1
SCHEMBL1821334 0.80 OPRM1 (0.36) OPRM1FDPSLMNADNM1SMPD1
SCHEMBL1821751 0.78 OPRM1 (0.39) OPRM1FDPSTP53LMNADNM1
SCHEMBL305600 0.77 OPRM1 (0.42) OPRM1FDPSTP53LMNADNM1
SCHEMBL1817984 0.77 OPRM1 (0.38) OPRM1FDPSTP53LMNADNM1
SCHEMBL1109616 0.76 OPRM1 (0.41) OPRM1FDPSLMNADNM1SMPD1
SCHEMBL1123629 0.76 OPRM1 (0.41) OPRM1FDPSTP53LMNADNM1
SCHEMBL1123106 0.76 OPRM1 (0.41) OPRM1FDPSTP53LMNA
SCHEMBL2580819 0.76 OPRM1 (0.41) OPRM1FDPSLMNADNM1SMPD1
SCHEMBL6521708 0.76 OPRM1 (0.41) OPRM1FDPSLMNADNM1SMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9181356-B2 Hydrogenation catalyst composition and hydrogenation method thereof TSRC CORPORATION (TW) 2015-11-10 US disclosed
EP-2316862-B1 Hydrogenation catalyst composition and hydrogenation method thereof TSRC CORP (TW) 2013-12-25 EP disclosed
CN-101829600-B Hydrogenation catalyst composition and hydrogenation method thereof TSRC CORP 2012-08-29 CN disclosed
US-20110105694-A1 HYDROGENATION CATALYST COMPOSITION AND HYDROGENATION METHOD THEREOF TSRC CORPORATION (TW) 2011-05-05 US disclosed
EP-2316862-A1 Hydrogenation catalyst composition and hydrogenation method thereof TSRC Corporation (TW) 2011-05-04 EP disclosed
CN-101829600-A Hydrogenation catalyst composition and hydrogenation method thereof TSRC CORP 2010-09-15 CN disclosed