Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31467962 | 0.87 | LTB4R (0.30) | — | |
| SCHEMBL830068 | 0.78 | — | — | |
| SCHEMBL31477101 | 0.76 | RPS6KB2 (0.43) | DAOMEN1KMT2A | |
| SCHEMBL2046838 | 0.75 | — | — | |
| SCHEMBL7389174 | 0.72 | — | — | |
| SCHEMBL11926430 | 0.72 | ALDH1A1 (0.38) | DAOMEN1KMT2A | |
| SCHEMBL217981 | 0.72 | — | — | |
| SCHEMBL3246236 | 0.72 | — | — | |
| SCHEMBL21962702 | 0.71 | — | — | |
| SCHEMBL1822842 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2315751-A1 | ALKYNYL ALCOHOLS AS KINASE INHIBITORS | Amgen Inc. (US) | 2011-05-04 | — | — | EP | disclosed |
| WO-2009158011-A1 | ALKYNYL ALCOHOLS AS KINASE INHIBITORS | AMGEN INC. (US) | 2009-12-30 | — | — | WO | disclosed |