Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10587173 | 0.96 | HRH3 (0.61) | HRH3ALDH1A1HDAC8HDAC6ALDH2 | |
| SCHEMBL7768079 | 0.87 | HRH3 (0.84) | HRH3HDAC8HDAC6PYCR1 | |
| SCHEMBL29369685 | 0.85 | ESR1 (0.55) | HRH3ALDH1A1ALDH2L3MBTL1KDM4E | |
| Phenol SCHEMBL29096006 | 0.85 | BCHE (0.55) | HRH3ALDH1A1BCHEACHEL3MBTL1 | |
| SCHEMBL1206711 | 0.82 | HRH3 (0.69) | HRH3ALDH1A1ALDH2BCHEACHE | |
| SCHEMBL9416575 | 0.81 | OPRM1 (0.53) | HRH3BCHEACHEL3MBTL1KDM4E | |
| SCHEMBL5593365 | 0.81 | HRH3 (0.67) | HRH3HDAC8HDAC6ACHEPYCR1 | |
| SCHEMBL5926009 | 0.80 | HRH3 (0.73) | HRH3HDAC8HDAC6PYCR1 | |
| SCHEMBL12680476 | 0.80 | HRH3 (1.00) | HRH3HDAC8HDAC6PYCR1 | |
| SCHEMBL3804172 | 0.79 | ALDH1A1 (0.52) | HRH3ALDH1A1ALDH2BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013019655-A2 | VIMENTIN AS A BIOMARKER FOR THE PROGRESSION OF MYELOPROLIFERATIVE NEOPLASMS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) | 2013-02-07 | — | — | WO | claimed |
| US-8367078-B2 | Kinase inhibitor compounds | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2013-02-05 | — | — | US | claimed |
| EP-2376425-A2 | KINASE INHIBITOR COMPOUNDS | University of Florida Research Foundation, Inc. (US) | 2011-10-19 | — | — | EP | claimed |
| WO-2010068710-A2 | KINASE INHIBITOR COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-06-17 | — | — | WO | claimed |
| WO-2006018089-A1 | OXIDATION COLORANTS COMPRISING DIAMINOBENZENE DERIVATIVES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2006-02-23 | — | — | WO | claimed |
| CN-116507331-A | TLR7/8 antagonists and uses thereof | 默克专利有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-109134336-B | Diaryl ether compound, preparation method and application thereof | 北京大学深圳研究生院 | 2021-08-03 | — | — | CN | disclosed |
| CN-110366571-A | Modified resin and hardening resin composition comprising the modified resin | 协立化学产业株式会社 | 2019-10-22 | — | — | CN | disclosed |
| CN-110366570-A | (methyl) acrylate and hardening resin composition comprising (methyl) acrylate | 协立化学产业株式会社 | 2019-10-22 | — | — | CN | disclosed |
| CN-107022762-B | The application of three amido fortified phenols or three amido substituted benzene thiophenols and tiny-etching treatment fluid | 广东光华科技股份有限公司 | 2019-07-30 | — | — | CN | disclosed |
| CN-109789067-A | Oxidizing agent composition containing surfactant in the packaging formed by the foil containing barrier layer | 汉高股份有限及两合公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-109689164-A | Thickened formulation containing oxidant in the packaging formed by the foil containing barrier layer | 汉高股份有限及两合公司 | 2019-04-26 | — | — | CN | disclosed |
| WO-1986006718-A1 | ANTIMALARIAL COMPOUNDS | THE AUSTRALIAN NATIONAL UNIVERSITY (AU) | 1986-11-20 | — | — | WO | disclosed |
| US-4542047-A | PRIMER, HOT MELT ADHESIVE | MONSANTO COMPANY (US) | 1985-09-17 | — | — | US | disclosed |
| EP-0145654-A1 | Method of lining the insides of pipes or parts of pipes | CIBA-GEIGY AG (CH) | 1985-06-19 | — | — | EP | disclosed |
| US-4482604-A | HOT MELT ADHESIVE | MONSANTO COMPANY (US) | 1984-11-13 | — | — | US | disclosed |
| EP-0118408-A1 | Bonded reinforced plastic structures | MONSANTO COMPANY (US) | 1984-09-12 | — | — | EP | disclosed |
| US-4391805-A | FUNGICIDES, ANTIPROTOZOA AGENTS, BACTERICIDWS | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-07-05 | — | — | US | disclosed |
| EP-0050298-A2 | 1-(1,3-Dioxolan-2-ylmethyl) azoles, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-04-28 | — | — | EP | disclosed |
| US-4215229-A | AMNNICH REACTION, HYDROGENOLYSIS | KOPPERS COMPANY, INC. (US) | 1980-07-29 | — | — | US | disclosed |