Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.55 |
| ▸ | PPARA | Q07869 | 17/20 | 0.55 |
| ▸ | PPARD | Q03181 | 3/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1338568 | 0.87 | PPARG (0.64) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL6076509 | 0.82 | PPARG (0.54) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL542828 | 0.82 | PPARG (0.62) | PPARGPPARAPPARDPGRADORA3 | |
| Ethane SCHEMBL1834451 | 0.79 | PPARA (0.63) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL1338522 | 0.79 | PPARG (0.52) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL542868 | 0.78 | PPARG (0.61) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL6076201 | 0.78 | PPARG (0.44) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL1338528 | 0.78 | PPARG (0.59) | PPARGPPARAPPARD | |
| SCHEMBL1822677 | 0.78 | PGR (0.70) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL543892 | 0.77 | PPARA (0.60) | PPARGPPARAPPARDPGRADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1414439-B1 | NOVEL PYRROLES HAVING HYPOLIPIDEMIC HYPOCHOLESTEREMIC ACTIVITIES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN MEDICINE | CADILA HEALTHCARE LTD (IN) | 2011-05-04 | — | — | EP | disclosed |