SCHEMBL1822701

SCHEMBL1822701

CCCOC(C)(OCCC)[SiH2]CCCNCCC[SiH2]C(C)(OCCC)OCCC

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
TSHR P16473 1/20 0.34
MEN1 O00255 1/20 0.30
GLA P06280 1/20 0.30
CYP2C19 P33261 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27791899 0.87
SCHEMBL705155 0.86
SCHEMBL705784 0.86
SCHEMBL27792163 0.85
SCHEMBL16192426 0.83 TSHR (0.38) ALDH1A1TSHR
SCHEMBL703247 0.81
SCHEMBL16862742 0.78 ALDH1A1 (0.36) ALDH1A1TSHRMEN1GLACYP2C19
SCHEMBL707074 0.75 ADRB2 (0.33) TSHR
SCHEMBL703940 0.75 ADRB2 (0.33) TSHR
SCHEMBL1819647 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9181356-B2 Hydrogenation catalyst composition and hydrogenation method thereof TSRC CORPORATION (TW) 2015-11-10 US disclosed
EP-2316862-B1 Hydrogenation catalyst composition and hydrogenation method thereof TSRC CORP (TW) 2013-12-25 EP disclosed
CN-101829600-B Hydrogenation catalyst composition and hydrogenation method thereof TSRC CORP 2012-08-29 CN disclosed
US-20110105694-A1 HYDROGENATION CATALYST COMPOSITION AND HYDROGENATION METHOD THEREOF TSRC CORPORATION (TW) 2011-05-05 US disclosed
EP-2316862-A1 Hydrogenation catalyst composition and hydrogenation method thereof TSRC Corporation (TW) 2011-05-04 EP disclosed
CN-101829600-A Hydrogenation catalyst composition and hydrogenation method thereof TSRC CORP 2010-09-15 CN disclosed