Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | APEX1 | P27695 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | GPR17 | Q13304 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 3/20 | 0.32 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.32 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.32 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.32 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18229762 | 0.81 | STAT3 (0.44) | STAT3STAT1KDM4EAPEX1CHRM1 | |
| SCHEMBL9450931 | 0.76 | STAT3 (0.46) | STAT3STAT1KDM4EALDH1A1EGFR | |
| SCHEMBL6416150 | 0.75 | CHRM1 (0.38) | STAT3STAT1KDM4EAPEX1CHRM1 | |
| SCHEMBL5072857 | 0.74 | HSD17B10 (0.34) | APEX1GPR17EGFRHPGDHSD17B10 | |
| Phenyl Propionic Acid SCHEMBL27936217 | 0.74 | KEAP1 (0.56) | KDM4ECHRM1 | |
| SCHEMBL18229766 | 0.73 | FABP3 (0.38) | KDM4EAPEX1GPR17ALDH1A1HPGD | |
| SCHEMBL6410839 | 0.73 | GPR17 (0.33) | KDM4EAPEX1CHRM1GPR17EGFR | |
| SCHEMBL5533945 | 0.72 | STAT3 (0.49) | STAT3STAT1 | |
| Butyric Acid SCHEMBL28119498 | 0.72 | FFAR3 (0.42) | STAT3STAT1KDM4EAPEX1CHRM1 | |
| Malonic Acid SCHEMBL5133240 | 0.71 | STAT3 (0.36) | STAT3STAT1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10900071-B2 | Identification of genetic modifications | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2021-01-26 | — | — | US | disclosed |
| US-20190040457-A1 | IDENTIFICATION OF GENETIC MODIFICATIONS | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2019-02-07 | — | — | US | disclosed |
| EP-3307755-A1 | IDENTIFICATION OF GENETIC MODIFICATIONS | Wake Forest University Health Sciences (US) | 2018-04-18 | — | — | EP | disclosed |
| WO-2016183289-A1 | IDENTIFICATION OF GENETIC MODIFICATIONS | WAKE FOREST UNIVERSITY HEALTH SERVICES (US) | 2016-11-17 | — | — | WO | disclosed |