Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | APEX1 | P27695 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CNKSR1 | Q969H4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenyl Propionic Acid SCHEMBL27936217 | 0.76 | KEAP1 (0.56) | KDM4EHDAC6SMN1; SMN2 | |
| SCHEMBL6410839 | 0.74 | GPR17 (0.33) | GPR17APEX1KDM4E | |
| Butyric Acid SCHEMBL28119498 | 0.74 | FFAR3 (0.42) | ALDH1A1APEX1KDM4ELMNAKMT2A | |
| SCHEMBL6416150 | 0.74 | CHRM1 (0.38) | GPR17ALDH1A1APEX1KDM4EPOLB | |
| SCHEMBL18229760 | 0.73 | STAT3 (0.36) | GPR17ALDH1A1APEX1KDM4EHPGD | |
| Malonic Acid SCHEMBL5133240 | 0.73 | STAT3 (0.36) | ALDH1A1KDM4EKMT2AHPGDHSD17B10 | |
| Malonic Acid SCHEMBL27560828 | 0.73 | STAT3 (0.36) | ALDH1A1KDM4EKMT2AHPGDHSD17B10 | |
| Glycine SCHEMBL14801761 | 0.72 | GLRA1 (0.36) | ALDH1A1 | |
| Propionic Acid SCHEMBL27439210 | 0.72 | FFAR3 (0.36) | LMNAKMT2APIN1RAB9ASMN1; SMN2 | |
| Propionic Acid SCHEMBL2502176 | 0.72 | FFAR3 (0.36) | LMNAKMT2APIN1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10900071-B2 | Identification of genetic modifications | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2021-01-26 | — | — | US | disclosed |
| US-20190040457-A1 | IDENTIFICATION OF GENETIC MODIFICATIONS | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2019-02-07 | — | — | US | disclosed |
| EP-3307755-A1 | IDENTIFICATION OF GENETIC MODIFICATIONS | Wake Forest University Health Sciences (US) | 2018-04-18 | — | — | EP | disclosed |
| WO-2016183289-A1 | IDENTIFICATION OF GENETIC MODIFICATIONS | WAKE FOREST UNIVERSITY HEALTH SERVICES (US) | 2016-11-17 | — | — | WO | disclosed |