Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.46 |
| ▸ | CD38 | P28907 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | KDM4B | O94953 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F12 | P00748 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18230473 | 0.84 | TRPV1 (0.50) | TRPV1ADORA2AADORA1TRPV4MEN1 | |
| SCHEMBL18230521 | 0.82 | TRPV1 (0.59) | TRPV1ADORA2AADORA1MEN1MAPT | |
| SCHEMBL18230379 | 0.82 | ADORA2A (0.71) | TRPV1ADORA2AADORA1MEN1MAPT | |
| SCHEMBL18230280 | 0.81 | TRPV1 (0.58) | TRPV1ADORA2AADORA1MEN1MAPT | |
| SCHEMBL18230400 | 0.80 | TRPV4 (0.56) | TRPV1ADORA2AADORA1TRPV4MEN1 | |
| SCHEMBL18230420 | 0.80 | TRPV4 (0.70) | TRPV1ADORA2AADORA1TRPV4MEN1 | |
| SCHEMBL18230421 | 0.80 | ADORA1 (0.62) | TRPV1ADORA2AADORA1MEN1MAPT | |
| SCHEMBL18230278 | 0.80 | TRPV1 (0.57) | TRPV1ADORA2AADORA1MEN1MAPT | |
| SCHEMBL18230245 | 0.80 | TRPV1 (0.57) | TRPV1ADORA2AADORA1MEN1MAPT | |
| SCHEMBL18230523 | 0.80 | TRPV1 (0.57) | TRPV1ADORA2AADORA1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |