Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.56 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.49 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18230420 | 0.89 | TRPV4 (0.70) | TRPV4LRRK2MAPTSMN1; SMN2SCN9A | |
| SCHEMBL18230451 | 0.87 | TRPV4 (0.59) | TRPV4MAPTSMN1; SMN2TRPV1ADORA2A | |
| SCHEMBL18230336 | 0.85 | LRRK2 (0.48) | TRPV4LRRK2MAPTSTAT3SMN1; SMN2 | |
| SCHEMBL18230465 | 0.81 | TRPV1 (0.48) | LRRK2MAPTSMN1; SMN2SCN9ASCN5A | |
| SCHEMBL18230473 | 0.81 | TRPV1 (0.50) | TRPV4MAPTSTAT3SMN1; SMN2TRPV1 | |
| SCHEMBL18230379 | 0.81 | ADORA2A (0.71) | MAPTSTAT3SMN1; SMN2TRPV1ADORA2A | |
| SCHEMBL18230521 | 0.81 | TRPV1 (0.59) | MAPTSTAT3SMN1; SMN2TRPV1ADORA2A | |
| SCHEMBL18230474 | 0.80 | TRPV1 (0.52) | TRPV4MAPTSMN1; SMN2TRPV1ADORA2A | |
| SCHEMBL18230280 | 0.80 | TRPV1 (0.58) | MAPTSTAT3SMN1; SMN2TRPV1ADORA2A | |
| SCHEMBL18230245 | 0.79 | TRPV1 (0.57) | MAPTSTAT3SMN1; SMN2TRPV1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |