Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 8/20 | 0.68 |
| ▸ | MME | P08473 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 3/20 | 0.50 |
| ▸ | CPA1 | P15085 | 3/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1824158 | 1.00 | FPR2 (0.68) | FPR2MMEMEN1KMT2AACE | |
| SCHEMBL1823125 | 1.00 | FPR2 (0.68) | FPR2MMEMEN1KMT2AACE | |
| SCHEMBL7677296 | 0.91 | FPR2 (0.56) | FPR2MEN1KMT2AACE | |
| SCHEMBL7677287 | 0.91 | FPR2 (0.56) | FPR2MEN1KMT2AACE | |
| SCHEMBL7673496 | 0.91 | FPR2 (0.56) | FPR2MEN1KMT2AACE | |
| SCHEMBL4415553 | 0.90 | NOS2 (0.58) | FPR2CA1CA2 | |
| SCHEMBL4415551 | 0.90 | NOS2 (0.58) | FPR2CA1CA2 | |
| SCHEMBL7674471 | 0.90 | NOS2 (0.58) | FPR2CA1CA2 | |
| SCHEMBL1824098 | 0.84 | GRN (0.61) | FPR2MMECA1CA2 | |
| SCHEMBL1824097 | 0.84 | GRN (0.61) | FPR2MMECA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2123328-A1 | Galanthamine derivatives, methods for their obtaining and use | Sopharma AD (BG) | 2009-11-25 | — | — | EP | claimed |
| EP-2123328-B1 | Galanthamine derivatives, methods for their obtaining and use | SOPHARMA AD (BG) | 2011-05-04 | — | — | EP | disclosed |
| EP-2123328-A1 | Galanthamine derivatives, methods for their obtaining and use | Sopharma AD (BG) | 2009-11-25 | — | — | EP | disclosed |