Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.42 |
| ▸ | ENPP1 | P22413 | 4/20 | 0.42 |
| ▸ | ENPP3 | O14638 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1823302 | 0.91 | P2RX7 (0.46) | P2RX7CTSSCTSKALDH1A1TSHR | |
| SCHEMBL1825145 | 0.90 | P2RX7 (0.45) | P2RX7CTSSCTSKALDH1A1TSHR | |
| SCHEMBL13345184 | 0.90 | P2RX7 (0.45) | P2RX7CTSSCTSKALDH1A1TSHR | |
| SCHEMBL3568238 | 0.88 | P2RX7 (0.46) | P2RX7CTSSCTSKALDH1A1TSHR | |
| SCHEMBL1824289 | 0.87 | P2RX7 (0.44) | P2RX7CTSSCTSKALDH1A1TSHR | |
| SCHEMBL1823084 | 0.86 | P2RX7 (0.45) | P2RX7ALDH1A1TSHRMEN1MAPT | |
| SCHEMBL1826243 | 0.86 | CNR1 (0.46) | P2RX7ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL12195416 | 0.85 | CTSS (0.52) | CTSSCTSKALDH1A1TSHRPPARG | |
| SCHEMBL8513252 | 0.85 | CTSS (0.52) | CTSSCTSKALDH1A1TSHRPPARG | |
| SCHEMBL27159559 | 0.85 | CTSS (0.52) | CTSSCTSKALDH1A1TSHRPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2161254-B1 | Intermediate for preparing a biaryl compound | SUMITOMO CHEMICAL CO (JP) | 2014-08-13 | — | — | EP | disclosed |
| EP-1481967-B1 | PROCESS FOR THE PREPARATION OF BIARYL COMPOUNDS | SUMITOMO CHEMICAL CO (JP) | 2011-05-04 | — | — | EP | disclosed |
| EP-2161254-A1 | Intermediate for preparing a biaryl compound | Sumitomo Chemical Company, Limited (JP) | 2010-03-10 | — | — | EP | disclosed |