SCHEMBL18232178

SCHEMBL18232178

CC(C)(C)c1ccc2c3ccccc3n(-c3ccc(-c4ccccc4)cc3)c2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.49
ATM Q13315 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
PPARG P37231 4/20 0.42
KIF11 P52732 3/20 0.41
HDAC4 P56524 1/20 0.40
PPARA Q07869 2/20 0.40
ALDH1A1 P00352 1/20 0.40
MAPT P10636 1/20 0.40
MAPK1 P28482 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
KMT2A Q03164 1/20 0.38
RXRA P19793 1/20 0.37
RXRB P28702 1/20 0.37
MAT2A P31153 1/20 0.36
MDM2 Q00987 1/20 0.36
IL1R1 P14778 1/20 0.35
TSPO P30536 1/20 0.35
PTGES O14684 1/20 0.35
AKR1C4 P17516 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28063975 0.95 KDM4E (0.40) KDM4EATML3MBTL1PPARGKIF11
SCHEMBL25847350 0.93 KDM4E (0.47) KDM4EATML3MBTL1PPARGKIF11
SCHEMBL13542514 0.93 KDM4E (0.50) KDM4EATML3MBTL1PPARGKIF11
SCHEMBL23184829 0.92 KDM4E (0.50) KDM4EATML3MBTL1PPARGKIF11
SCHEMBL12354079 0.91 KDM4E (0.60) KDM4EATML3MBTL1PPARGKIF11
SCHEMBL25708812 0.91 L3MBTL1 (0.50) KDM4EATML3MBTL1PPARGKIF11
SCHEMBL10206222 0.90 KDM4E (0.43) KDM4EATML3MBTL1PPARGKIF11
SCHEMBL13132840 0.90 KDM4E (0.43) KDM4EATML3MBTL1PPARGKIF11
SCHEMBL25685920 0.90 KDM4E (0.43) KDM4EATML3MBTL1PPARGKIF11
SCHEMBL13174342 0.90 KDM4E (0.43) KDM4EATML3MBTL1PPARGKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11746093-B2 Nitrogen-containing compound, electronic element, and electronic device SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-09-05 US disclosed
US-11746093-B2 Nitrogen-containing compound, electronic element, and electronic device SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-09-05 US disclosed
US-20230192627-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed
US-20230192627-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed
US-9947878-B2 Organic light-emitting device LG CHEM, LTD. (KR) 2018-04-17 US disclosed
US-20170012217-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2017-01-12 US disclosed
US-20160336518-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2016-11-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11746093-B2 Nitrogen-containing compound, electronic element, and electronic device SLC43A1, SLC7A5, L1CAM KDM4E 1666/4885ATM 2086/4885L3MBTL1 1030/4885
US-20230192627-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE SLC43A1, SLC7A5, L1CAM KDM4E 1666/4885ATM 2086/4885L3MBTL1 1030/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.