Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 10/20 | 0.34 |
| ▸ | KRAS | P01116 | 5/20 | 0.34 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | TET3 | O43151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.31 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.31 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.31 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.31 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | BLK | P51451 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10138954 | 0.82 | — | — | |
| SCHEMBL25467314 | 0.78 | TEAD1 (0.36) | TEAD1JAK3KRASACHETET3 | |
| SCHEMBL22719868 | 0.78 | TEAD1 (0.36) | TEAD1JAK3KRASACHETET3 | |
| SCHEMBL25205555 | 0.78 | JAK3 (0.45) | JAK3ACHEKMT2A | |
| SCHEMBL20383195 | 0.78 | TEAD1 (0.36) | TEAD1JAK3KRASACHETET3 | |
| SCHEMBL30834535 | 0.77 | JAK3 (0.38) | JAK3KRASACHEBTK | |
| SCHEMBL25976400 | 0.77 | JAK3 (0.38) | TEAD1JAK3KRASACHEBTK | |
| SCHEMBL9700171 | 0.77 | SMN1; SMN2 (0.46) | KMT2A | |
| SCHEMBL17443386 | 0.75 | — | — | |
| SCHEMBL29197336 | 0.74 | KRAS (0.34) | TEAD1JAK3KRASACHETET3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183094-A1 | BICYCLIC COMPOUNDS | KALYRA PHARMACEUTICALS, INC. (US) | 2016-11-17 | — | — | WO | disclosed |