Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 7/20 | 0.34 |
| ▸ | JAK3 | P52333 | 6/20 | 0.33 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | TET3 | O43151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.31 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.31 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.31 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.31 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 2/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | BLK | P51451 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27906966 | 0.80 | KRAS (0.35) | KRASJAK3ACHETET3KMT2A | |
| SCHEMBL10138954 | 0.77 | — | — | |
| SCHEMBL17443386 | 0.75 | — | — | |
| SCHEMBL25205555 | 0.74 | JAK3 (0.45) | JAK3ACHEKMT2AALDH1A1 | |
| SCHEMBL18232330 | 0.74 | TEAD1 (0.36) | KRASJAK3ACHETET3KMT2A | |
| SCHEMBL21393276 | 0.73 | TEAD1 (0.36) | KRASJAK3ACHETET3KMT2A | |
| SCHEMBL9464253 | 0.73 | KRAS (0.36) | KRASJAK3ACHETET3KMT2A | |
| SCHEMBL22212872 | 0.73 | — | — | |
| SCHEMBL22631197 | 0.73 | CHRNB2 (0.38) | KRASJAK3 | |
| SCHEMBL16385269 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117940425-A | HER2 mutation inhibitors | 阿雷生物药品公司 | 2024-04-26 | — | — | CN | claimed |
| CN-117940425-A | HER2 mutation inhibitors | 阿雷生物药品公司 | 2024-04-26 | — | — | CN | disclosed |