Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 12/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.33 |
| ▸ | CHRNB3 | Q05901 | 5/20 | 0.33 |
| ▸ | CHRNA6 | Q15825 | 5/20 | 0.33 |
| ▸ | KRAS | P01116 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10138954 | 0.80 | — | — | |
| SCHEMBL21794792 | 0.79 | BIRC2 (0.42) | JAK3CHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL21543186 | 0.79 | BIRC2 (0.42) | JAK3CHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL20315135 | 0.79 | BIRC2 (0.42) | JAK3CHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL25205555 | 0.77 | JAK3 (0.45) | JAK3ACHE | |
| SCHEMBL18232330 | 0.77 | TEAD1 (0.36) | JAK3KRASBTKACHE | |
| SCHEMBL25976400 | 0.75 | JAK3 (0.38) | JAK3KRASBTKACHE | |
| SCHEMBL9700171 | 0.75 | SMN1; SMN2 (0.46) | — | |
| Nanofin SCHEMBL29027515 | 0.74 | CYP2C9 (0.43) | JAK3BTK | |
| SCHEMBL21543557 | 0.73 | CHRNB2 (0.38) | CHRNB2CHRNA3CHRNA4CHRNB3CHRNA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112119075-B | Condensed ring compound | 豪夫迈·罗氏有限公司 | 2024-03-12 | — | — | CN | disclosed |