Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | CDK2 | P24941 | 2/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18233041 | 0.84 | KMT2A (0.55) | KMT2APOLBSMN1; SMN2CDK2CCNA2 | |
| SCHEMBL18415346 | 0.83 | KMT2A (0.60) | KMT2APOLBSMN1; SMN2CDK2CCNA2 | |
| SCHEMBL18236174 | 0.80 | ALPL (0.41) | KMT2ASMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL18704456 | 0.79 | KMT2A (0.60) | KMT2APOLBSMN1; SMN2CDK2CCNA2 | |
| SCHEMBL23648057 | 0.79 | CHEK1 (0.56) | KMT2APOLBSMN1; SMN2CDK2CCNA2 | |
| SCHEMBL26784594 | 0.79 | HCAR3 (0.59) | KMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL18407359 | 0.79 | KMT2A (0.56) | KMT2APOLBSMN1; SMN2CDK2CCNA2 | |
| SCHEMBL18415352 | 0.75 | KMT2A (0.51) | KMT2APOLBSMN1; SMN2AURKARPS6KB1 | |
| SCHEMBL5012183 | 0.74 | NPC1 (0.55) | KMT2ARAB9ANPC1ALDH1A1BDKRB1 | |
| SCHEMBL7852787 | 0.74 | KMT2A (1.00) | KMT2APOLBSMN1; SMN2CDK2CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160332996-A1 | Hepatitis B Antiviral Agents | ENANTA PHARMACEUTICALS, INC. | 2016-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160332996-A1 | Hepatitis B Antiviral Agents | ZC3HAV1, ZC3HAV1L, HAVCR2 | KMT2A 2729/4885POLB 621/4885SMN1; SMN2 4775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.