SCHEMBL1823712

SCHEMBL1823712

O=C1CCCCCN1C(=O)c1ccc(C(=O)N2CCCCCC2=O)cc1

nearest known ligand 0.77

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MITF O75030 1/20 0.77
SMN1; SMN2 Q16637 1/20 0.77
KDM4E B2RXH2 1/20 0.66
MEN1 O00255 1/20 0.66
CYP1A2 P05177 1/20 0.66
CYP2D6 P10635 1/20 0.66
MAPT P10636 1/20 0.66
THRB P10828 1/20 0.66
CYP2C9 P11712 1/20 0.66
CYP2C19 P33261 1/20 0.66
RECQL P46063 1/20 0.66
BLM P54132 1/20 0.66
KMT2A Q03164 1/20 0.66
ALDH1A1 P00352 4/20 0.53
HPGD P15428 3/20 0.53
AVPR2 P30518 10/20 0.49
AVPR1A P37288 9/20 0.49
OXTR P30559 4/20 0.49
LMNA P02545 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1948086 1.00 MITF (0.77) MITFSMN1; SMN2KDM4EMEN1CYP1A2
SCHEMBL8382911 1.00 MITF (0.77) MITFSMN1; SMN2KDM4EMEN1CYP1A2
SCHEMBL8380777 1.00 MITF (0.77) MITFSMN1; SMN2KDM4EMEN1CYP1A2
SCHEMBL8379314 1.00 MITF (0.77) MITFSMN1; SMN2KDM4EMEN1CYP1A2
SCHEMBL8377415 0.98 MITF (0.73) MITFSMN1; SMN2KDM4EMEN1CYP1A2
SCHEMBL5182886 0.92 KMT2A (0.75) MITFSMN1; SMN2KDM4EMEN1CYP1A2
SCHEMBL8539282 0.92 MITF (0.67) MITFSMN1; SMN2KDM4EMEN1CYP1A2
SCHEMBL5182458 0.92 MITF (0.67) MITFSMN1; SMN2KDM4EMEN1CYP1A2
SCHEMBL5575714 0.92 MITF (0.67) MITFSMN1; SMN2KDM4EMEN1CYP1A2
SCHEMBL8380683 0.91 SMN1; SMN2 (0.66) MITFSMN1; SMN2KDM4EMEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1467775-B1 MEDICAL DEVICES EMPLOYING CHAIN EXTENDED POLYMERS BOSTON SCIENT LTD (BB) 2011-05-04 EP claimed
EP-0436802-A2 Capped polyphenylenether HÜLS AKTIENGESELLSCHAFT (DE) 1991-07-17 EP claimed
JP-3062826-A None JP disclosed
JP-63099228-A None JP disclosed
JP-1236238-A None JP disclosed
WO-2023023446-A1 HIGH MOLECULAR WEIGHT POLYESTERAMIDES SOLUTIA INC. (US) 2023-02-23 WO disclosed
EP-3121208-A1 POLYMERIC MATERIALS Commonwealth Scientific and Industrial Research Organisation (AU) 2017-01-25 EP disclosed
EP-1841824-B1 HIGHLY VISCOSE THERMOPLASTIC POLYMER-BASED MOULDING COMPOUNDS AND THE USE THEREOF EMS CHEMIE AG (CH) 2011-09-28 EP disclosed
EP-1643019-B1 POLYETHER ESTER ELASTIC FIBER AND FABRICS AND CLOTHES MADE BY USING THE SAME TEIJIN FIBERS LTD (JP) 2010-09-22 EP disclosed
US-20080071009-A1 improve melt strength and melt viscosity of PET polyesters by branching with pentaerythritol in presence of chain coupling agent dianhydride or phosphite, a phosphinate or a phosphonate and carrier polymer CIBA CORP. 2008-03-20 US disclosed
EP-1841824-A1 HIGHLY VISCOSE THERMOPLASTIC POLYMER-BASED MOULDING COMPOUNDS AND THE USE THEREOF EMS-CHEMIE AG (CH) 2007-10-10 EP disclosed
JP-H0362826-A PRODUCTION OF POLYAMIDE FORM TEIJIN LTD 1991-03-18 JP disclosed
JP-H01236238-A PRODUCTION OF POLYAMIDE OF INCREASED TERMINAL CARBOXYL GROUP CONTENT TEIJIN LTD 1989-09-21 JP disclosed
JP-S6399228-A PRODUCTION OF POLYESTER HAVING HIGH POLYMERIZATION DEGREE TEIJIN LTD 1988-04-30 JP disclosed
US-4665410-A THERMOGRAPHY RICOH COMPANY, LTD. (JP) 1987-05-12 US disclosed
US-4663641-A LEUCO DYES; DECOLORIZING AGENTS, PIPERAZINE COMPOUND; AMIDES AND TERTIARY AMINES RICOH COMPANY, LTD. (JP) 1987-05-05 US disclosed
US-4613878-A DECOLORIZING AGENT COMPRISING AROMATIC DIAMIDE OR PIPERAZINE DERIVATIVE, HAVING TWO ACYLAMINO GROUPS RICOH COMPANY, LTD. (JP) 1986-09-23 US disclosed
US-4200731-A REACTION WITH N-BENZOYLLACTAM OR N-BENZOYLPHTHALIMIDE TO FORM BENZOYL ENDCAPS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1980-04-29 US disclosed
US-4153582-A Method for the preparation of polymers of lactams having an enhanced electric conductivity CESKOSLOVENSKA AKADEMIE VED (CS) 1979-05-08 US disclosed
US-4049611-A PLASTICIZERS MONSANTO COMPANY (US) 1977-09-20 US disclosed