SCHEMBL8539282

SCHEMBL8539282

O=C1CCCCCN1C(=O)c1ccc(Cl)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MITF O75030 1/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
AVPR2 P30518 2/20 0.61
AVPR1A P37288 1/20 0.61
ALDH1A1 P00352 5/20 0.58
MAPT P10636 3/20 0.57
KMT2A Q03164 3/20 0.57
MEN1 O00255 2/20 0.57
KDM4E B2RXH2 1/20 0.57
CYP1A2 P05177 1/20 0.57
CYP2D6 P10635 1/20 0.57
THRB P10828 1/20 0.57
CYP2C9 P11712 1/20 0.57
CYP2C19 P33261 1/20 0.57
RECQL P46063 1/20 0.57
BLM P54132 1/20 0.57
TP53 P04637 1/20 0.53
MDM2 Q00987 1/20 0.53
HSD17B10 Q99714 1/20 0.49
RAB9A P51151 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8543824 0.98 MITF (0.64) MITFSMN1; SMN2AVPR2AVPR1AALDH1A1
SCHEMBL1948086 0.92 MITF (0.77) MITFSMN1; SMN2AVPR2AVPR1AALDH1A1
SCHEMBL8382911 0.92 MITF (0.77) MITFSMN1; SMN2AVPR2AVPR1AALDH1A1
SCHEMBL1823712 0.92 MITF (0.77) MITFSMN1; SMN2AVPR2AVPR1AALDH1A1
SCHEMBL8379314 0.92 MITF (0.77) MITFSMN1; SMN2AVPR2AVPR1AALDH1A1
SCHEMBL8380777 0.92 MITF (0.77) MITFSMN1; SMN2AVPR2AVPR1AALDH1A1
SCHEMBL8377415 0.90 MITF (0.73) MITFSMN1; SMN2AVPR2AVPR1AALDH1A1
SCHEMBL23387913 0.84 MITF (0.63) MITFSMN1; SMN2AVPR2AVPR1AALDH1A1
SCHEMBL5182886 0.84 KMT2A (0.75) MITFSMN1; SMN2AVPR2AVPR1AALDH1A1
SCHEMBL8539334 0.84 MITF (0.55) MITFSMN1; SMN2AVPR2AVPR1AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5753138-A COMPRISING SPECIFIED BLEACH ACTIVATOR PRODUCING PERACID ON HYDROLYSIS, HYDROGEN PEROXIDE SOURCE THE PROCTER & GAMBLE COMPANY (US) 1998-05-19 US disclosed
CN-1173202-A Bleaching detergent compositions comprising bleach activators effective at low perhydroxyl concentrations PROCTER & GAMBLE (US) 1998-02-11 CN disclosed
CN-1173200-A Bleaching compositions and bleach-additives comprising bleach activators effective at low perhydroxyl concentrations PROCTER & GAMBLE (US) 1998-02-11 CN disclosed
CN-1173201-A Use of bleach activators for low perhydroxyl concentrations PROCTER & GAMBLE (US) 1998-02-11 CN disclosed
EP-0792345-A1 BLEACHING COMPOSITIONS AND BLEACH-ADDITIVES COMPRISING BLEACH ACTIVATORS EFFECTIVE AT LOW PERHYDROXYL CONCENTRATIONS THE PROCTER & GAMBLE COMPANY (US) 1997-09-03 EP disclosed
EP-0792343-A1 USE OF BLEACH ACTIVATORS FOR LOW PERHYDROXYL CONCENTRATIONS THE PROCTER & GAMBLE COMPANY (US) 1997-09-03 EP disclosed
EP-0792344-A1 BLEACHING DETERGENT COMPOSITIONS COMPRISING BLEACH ACTIVATORS EFFECTIVE AT LOW PERHYDROXYL CONCENTRATIONS THE PROCTER & GAMBLE COMPANY (US) 1997-09-03 EP disclosed
US-5635104-A Bleaching solutions and method utilizing selected bleach activators effective at low perhydroxyl concentrations THE PROCTER & GAMBLE COMPANY (US) 1997-06-03 US disclosed
WO-1996016157-A1 BLEACHING DETERGENT COMPOSITIONS COMPRISING BLEACH ACTIVATORS EFFECTIVE AT LOW PERHYDROXYL CONCENTRATIONS THE PROCTER & GAMBLE COMPANY (US) 1996-05-30 WO disclosed
WO-1996016156-A1 USE OF BLEACH ACTIVATORS FOR LOW PERHYDROXYL CONCENTRATIONS THE PROCTER & GAMBLE COMPANY (US) 1996-05-30 WO disclosed
WO-1996016155-A1 BLEACHING COMPOSITIONS AND BLEACH-ADDITIVES COMPRISING BLEACH ACTIVATORS EFFECTIVE AT LOW PERHYDROXYL CONCENTRATIONS THE PROCTER & GAMBLE COMPANY (US) 1996-05-30 WO disclosed