Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.35 |
| ▸ | BPTF | Q12830 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | ACACA | Q13085 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18237334 | 0.87 | HASPIN (0.38) | PDE9AALDH1A1CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL10072551 | 0.79 | SMN1; SMN2 (0.51) | PDE9AALDH1A1CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL18237502 | 0.77 | ALDH1A1 (0.38) | PDE9AALDH1A1CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL19152811 | 0.77 | KAT2B (0.39) | ALDH1A1SMN1; SMN2BPTFKDM4CFEN1 | |
| SCHEMBL14966529 | 0.75 | CHEK1 (0.39) | ALDH1A1CYP1A2CYP2C19SMN1; SMN2PDE1C | |
| SCHEMBL17997563 | 0.75 | DYRK1A (0.39) | PDE9AHTR2AHTR2CHTR2BPDE1C | |
| SCHEMBL24835489 | 0.74 | HASPIN (0.34) | PDE9AALDH1A1CYP1A2CYP2C19HTR2A | |
| SCHEMBL15341744 | 0.73 | HTR2A (0.44) | HTR2AHTR2CHTR2BKDM4CFEN1 | |
| SCHEMBL18237503 | 0.72 | ALDH1A1 (0.34) | PDE9AALDH1A1CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL16339750 | 0.72 | HDAC8 (0.47) | PDE9AHTR2AHTR2CHTR2BPDE1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9931407-B2 | Silicon based drug conjugates and methods of using same | BLINKBIO, INC. (US) | 2018-04-03 | — | — | US | disclosed |
| US-20170202970-A1 | SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME | BLINKBIO, INC. | 2017-07-20 | — | — | US | disclosed |
| WO-2016183359-A1 | SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME | BLINKBIO, INC. (US) | 2016-11-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170202970-A1 | SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME | CD44, MSN, AS3MT | PDE9A 3304/4885ALDH1A1 2151/4885CYP1A2 3086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.