SCHEMBL1823786

SCHEMBL1823786

CCCN(Sc1nc2c(C)cccc2s1)C(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
GAA P10253 1/20 0.38
PKM P14618 1/20 0.36
MAPT P10636 7/20 0.36
GRIN2B Q13224 2/20 0.35
ACHE P22303 2/20 0.35
KDM4E B2RXH2 1/20 0.35
MITF O75030 1/20 0.35
HPGD P15428 1/20 0.35
LMNA P02545 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
ALOX15 P16050 1/20 0.34
MAPK1 P28482 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
RAB9A P51151 1/20 0.34
BCHE P06276 1/20 0.34
PAX8 Q06710 1/20 0.33
P2RX7 Q99572 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1820509 0.93 ALDH1A1 (0.40) ALDH1A1GAAPKMMAPTGRIN2B
SCHEMBL1821704 0.90 ALDH1A1 (0.44) ALDH1A1GAAPKMMAPTGRIN2B
SCHEMBL1820077 0.84 ALDH1A1 (0.41) ALDH1A1GAAPKMMAPTGRIN2B
SCHEMBL1193524 0.80 FBP1 (0.51) ALDH1A1MAPTKDM4EHPGDLMNA
SCHEMBL1818329 0.80 ALDH1A1 (0.47) ALDH1A1GAAPKMMAPTGRIN2B
SCHEMBL1821538 0.79 ALDH1A1 (0.41) ALDH1A1GAAPKMMAPTGRIN2B
SCHEMBL1821450 0.76 ALDH1A1 (0.44) ALDH1A1GAAPKMMAPTGRIN2B
SCHEMBL24602984 0.73 ALDH1A1 (0.53) ALDH1A1GAAPKMMAPTGRIN2B
SCHEMBL1193557 0.73 ALDH1A1 (0.49) ALDH1A1MAPTKDM4EHPGDLMNA
SCHEMBL546016 0.72 ALDH1A1 (0.59) ALDH1A1GAAPKMMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240317963-A1 RUBBER COMPOSITION FOR HOSE INNER TUBE, LAMINATED BODY, AND HOSE BRIDGESTONE CORPORATION (JP) 2024-09-26 US disclosed
US-20240240001-A1 RUBBER COMPOSITION FOR HOSE INNER TUBE, LAMINATED BODY, AND HOSE BRIDGESTONE CORPORATION (JP) 2024-07-18 US disclosed
EP-4378992-A1 RUBBER COMPOSITION FOR HOSE INNER TUBES, LAMINATE, AND HOSE BRIDGESTONE CORPORATION (JP) 2024-06-05 EP disclosed
EP-4378991-A1 RUBBER COMPOSITION FOR HOSE INNER TUBES, LAMINATE, AND HOSE BRIDGESTONE CORPORATION (JP) 2024-06-05 EP disclosed
EP-2447319-B1 RUBBER CRAWLER BRIDGESTONE CORP (JP) 2017-03-08 EP disclosed
US-8796387-B2 Rubber composition BRIDGESTONE CORPORATION (JP) 2014-08-05 US disclosed
US-8530549-B2 Rubber crawler BRIDGESTONE CORPORATION (JP) 2013-09-10 US disclosed
EP-2316879-B1 RUBBER COMPOSITION BRIDGESTONE CORP (JP) 2013-08-07 EP disclosed
US-20120108738-A1 RUBBER CRAWLER BRIDGESTONE CORPORTATION (JP) 2012-05-03 US disclosed
EP-2447319-A1 RUBBER CRAWLER Bridgestone Corporation (JP) 2012-05-02 EP disclosed
US-20110184109-A1 RUBBER COMPOSITION BRIDGESTONE CORPORATION (JP) 2011-07-28 US disclosed
US-20110172339-A1 RUBBER COMPOSITION BRIDGESTONE CORPORATION (JP) 2011-07-14 US disclosed
US-20110166277-A1 RUBBER COMPOSITION BRIDGESTONE CORPORATION (JP) 2011-07-07 US disclosed
EP-2316881-A1 RUBBER COMPOSITION Bridgestone Corporation (JP) 2011-05-04 EP disclosed
EP-2316879-A1 RUBBER COMPOSITION Bridgestone Corporation (JP) 2011-05-04 EP disclosed
EP-2316880-A1 RUBBER COMPOSITION Bridgestone Corporation (JP) 2011-05-04 EP disclosed