Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K7 | O43318 | 14/20 | 0.48 |
| ▸ | TAB1 | Q15750 | 14/20 | 0.48 |
| ▸ | CLK1 | P49759 | 3/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16949415 | 1.00 | MAP3K7 (0.48) | MAP3K7TAB1CLK1DYRK1AMAPK8 | |
| SCHEMBL4346952 | 0.81 | MAP3K7 (0.43) | MAP3K7TAB1CLK1DYRK1A | |
| SCHEMBL4346955 | 0.81 | MAP3K7 (0.43) | MAP3K7TAB1CLK1DYRK1A | |
| SCHEMBL16932988 | 0.80 | MAP3K7 (0.47) | MAP3K7TAB1 | |
| SCHEMBL16932989 | 0.80 | MAP3K7 (0.47) | MAP3K7TAB1 | |
| SCHEMBL16949265 | 0.80 | MAP3K7 (0.59) | MAP3K7TAB1 | |
| SCHEMBL18238757 | 0.80 | MAP3K7 (0.59) | MAP3K7TAB1 | |
| SCHEMBL4350414 | 0.78 | MAP3K7 (0.46) | MAP3K7TAB1 | |
| SCHEMBL4350420 | 0.78 | MAP3K7 (0.46) | MAP3K7TAB1 | |
| SCHEMBL4346854 | 0.78 | MAP3K7 (0.47) | MAP3K7TAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9499551-B2 | Substituted pyrrolo[2,3-b]pyridines for treating cancer or inflammatory diseases | CONFLUENCE LIFE SCIENCES, INC. (US) | 2016-11-22 | — | — | US | disclosed |