Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 2/20 | 0.38 |
| ▸ | KDM4B | O94953 | 2/20 | 0.38 |
| ▸ | KDM5C | P41229 | 2/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19152542 | 0.77 | CCR8 (0.55) | CCR8KMT2APDE3BPDE3AADORA2A | |
| SCHEMBL18237714 | 0.77 | KDM5B (0.44) | PDE3BPDE3AADORA2AADORA1KDM4A | |
| SCHEMBL13178567 | 0.75 | REN (0.43) | PDE3BPDE3ANUDT1AXLAHR | |
| SCHEMBL30740096 | 0.75 | CCR8 (0.57) | CCR8KMT2AADORA2AADORA1KDM4E | |
| SCHEMBL15367016 | 0.75 | CCR8 (0.57) | CCR8KMT2AADORA2AADORA1KDM4E | |
| SCHEMBL19131034 | 0.75 | CCR8 (0.52) | CCR8KMT2APDE3BPDE3AADORA2A | |
| SCHEMBL18239045 | 0.73 | CCR8 (0.37) | CCR8KMT2APDE3BPDE3AADORA2A | |
| SCHEMBL18238493 | 0.73 | PDE3B (0.47) | KMT2APDE3BPDE3AADORA2AADORA1 | |
| SCHEMBL22492418 | 0.70 | CCR8 (0.55) | CCR8KMT2AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL24835675 | 0.69 | PDE3B (0.54) | KMT2APDE3BPDE3AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183359-A1 | SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME | BLINKBIO, INC. (US) | 2016-11-17 | — | — | WO | disclosed |