Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 6/20 | 0.35 |
| ▸ | JAK1 | P23458 | 5/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 2/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19152784 | 0.77 | CCR8 (0.41) | CCR8KMT2AJAK2JAK1ADORA2A | |
| SCHEMBL2760379 | 0.75 | DYRK1A (0.53) | DYRK1AREN | |
| SCHEMBL18238494 | 0.73 | ADORA2A (0.40) | KMT2AJAK2JAK1ADORA2AADORA1 | |
| SCHEMBL19130905 | 0.73 | FFAR2 (0.40) | CCR8KMT2AJAK2JAK1ADORA2A | |
| SCHEMBL18238200 | 0.73 | CCR8 (0.50) | CCR8KMT2AADORA2AADORA1PDE3B | |
| SCHEMBL4006768 | 0.65 | TTBK1 (0.48) | JAK2JAK1 | |
| SCHEMBL13178567 | 0.65 | REN (0.43) | RENPDE3BPDE3A | |
| SCHEMBL17128274 | 0.65 | CCR8 (0.47) | CCR8KMT2AJAK2JAK1ADORA2A | |
| SCHEMBL18238493 | 0.63 | PDE3B (0.47) | KMT2AADORA2AADORA1PDE3BPDE3A | |
| SCHEMBL24908744 | 0.63 | PDPK1 (0.40) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183359-A1 | SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME | BLINKBIO, INC. (US) | 2016-11-17 | — | — | WO | disclosed |