SCHEMBL18239031

SCHEMBL18239031

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nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MME P08473 3/20 0.45
BMP1 P13497 3/20 0.43
ENPEP Q07075 3/20 0.43
BIRC2 Q13490 1/20 0.40
ECE1 P42892 1/20 0.40
MMP2 P08253 4/20 0.38
MMP1 P03956 3/20 0.38
MMP3 P08254 1/20 0.38
GNPAT O15228 1/20 0.38
PRSS1 P07477 1/20 0.38
TMPRSS15 P98073 1/20 0.38
FCER2 P06734 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13768731 0.82 MME (0.45) MMEBMP1BIRC2MMP2MMP1
SCHEMBL23380919 0.79 ECE1 (0.46) MMEBMP1ENPEPECE1MMP1
SCHEMBL9954794 0.79 MME (0.53) MMEBMP1ENPEPGNPATPRSS1
SCHEMBL19705674 0.79 NPY4R (0.43) BMP1
SCHEMBL18237378 0.79 NPY4R (0.43) BMP1
SCHEMBL5881138 0.78 NOD1 (0.48) MMEENPEPECE1GNPAT
SCHEMBL26081534 0.77 CA2 (0.43) BMP1ENPEPECE1GNPAT
SCHEMBL25978155 0.77 MME (0.46) MMEBMP1BIRC2MMP2MMP1
SCHEMBL27512389 0.77 CA2 (0.43) BMP1ENPEPECE1GNPAT
SCHEMBL10076073 0.77 CA2 (0.43) BMP1ENPEPECE1GNPAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016183359-A1 SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME BLINKBIO, INC. (US) 2016-11-17 WO disclosed