Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14438007 | 0.75 | CYP2A6 (0.31) | ADORA2AADORA1 | |
| SCHEMBL17344791 | 0.73 | ADORA3 (0.36) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL21230321 | 0.73 | ADORA2A (0.39) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL15980591 | 0.72 | ADORA2A (0.41) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL29559945 | 0.71 | DYRK1A (0.39) | ADORA2AADORA1 | |
| SCHEMBL9877773 | 0.71 | AXL (0.38) | ADORA2AADORA1 | |
| SCHEMBL24175501 | 0.70 | ADORA3 (0.33) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL15980639 | 0.70 | ADORA3 (0.33) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL18237916 | 0.70 | KDM4E (0.38) | KCNH2 | |
| SCHEMBL13058676 | 0.68 | PIK3CG (0.33) | ADORA3ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9931407-B2 | Silicon based drug conjugates and methods of using same | BLINKBIO, INC. (US) | 2018-04-03 | — | — | US | disclosed |
| US-20170202970-A1 | SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME | BLINKBIO, INC. | 2017-07-20 | — | — | US | disclosed |
| WO-2016183359-A1 | SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME | BLINKBIO, INC. (US) | 2016-11-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170202970-A1 | SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME | CD44, MSN, AS3MT | ADORA3 4145/4885ADORA2A 4582/4885ADORA2B 4655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.