SCHEMBL18239106

SCHEMBL18239106

C#CCOCC(COCC#C)(COCC#C)NC(=O)CCOCCOCCOCCOCCOCCOCCN

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19153627 0.94 TSHR (0.31) TSHR
SCHEMBL18237261 0.93 TSHR (0.33) TSHR
SCHEMBL24712356 0.89 TSHR (0.33) TSHR
SCHEMBL24297071 0.86
SCHEMBL19153178 0.86 TSHR (0.35) TSHR
SCHEMBL24513693 0.86 TSHR (0.35) TSHR
SCHEMBL21012062 0.86 TSHR (0.35) TSHR
SCHEMBL20386871 0.86 TSHR (0.35) TSHR
SCHEMBL25764285 0.82 L3MBTL1 (0.36) TSHR
SCHEMBL18227302 0.81 TSHR (0.32) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230000993-A1 SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME BLINKBIO INC (US) 2023-01-05 US disclosed
US-20230000993-A1 SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME BLINKBIO INC (US) 2023-01-05 US disclosed
US-11497757-B2 Silanol based therapeutic payloads BLINKBIO, INC. (US) 2022-11-15 US disclosed
US-20220184104-A1 SILANOL BASED THERAPEUTIC PAYLOADS BLINKBIO INC (US) 2022-06-16 US disclosed
US-20220184104-A1 SILANOL BASED THERAPEUTIC PAYLOADS BLINKBIO INC (US) 2022-06-16 US disclosed
US-11291731-B2 Silicon based drug conjugates and methods of using same BLINKBIO, INC. (US) 2022-04-05 US disclosed
US-20210161921-A1 Silanol Based Therapeutic Payloads BLINKBIO, INC. 2021-06-03 US disclosed
US-20210161921-A1 Silanol Based Therapeutic Payloads BLINKBIO, INC. 2021-06-03 US disclosed
US-10716801-B2 Silanol based therapeutic payloads BLINKBIO, INC. (US) 2020-07-21 US disclosed
US-10716801-B2 Silanol based therapeutic payloads BLINKBIO, INC. (US) 2020-07-21 US disclosed
US-10064880-B2 Silanol based therapeutic payloads BLINKBIO, INC. (US) 2018-09-04 US disclosed
US-20180200273-A1 Silanol Based Therapeutic Payloads BLINKBIO INC (US) 2018-07-19 US disclosed
US-20180200273-A1 Silanol Based Therapeutic Payloads BLINKBIO INC (US) 2018-07-19 US disclosed
US-9931407-B2 Silicon based drug conjugates and methods of using same BLINKBIO, INC. (US) 2018-04-03 US disclosed
US-9931407-B2 Silicon based drug conjugates and methods of using same BLINKBIO, INC. (US) 2018-04-03 US disclosed
WO-2017214491-A1 SILANOL BASED THERAPEUTIC PAYLOADS BLINKBIO, INC. (US) 2017-12-14 WO disclosed
WO-2017214491-A1 SILANOL BASED THERAPEUTIC PAYLOADS BLINKBIO, INC. (US) 2017-12-14 WO disclosed
US-20170202970-A1 SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME BLINKBIO, INC. 2017-07-20 US disclosed
US-20170202970-A1 SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME BLINKBIO, INC. 2017-07-20 US disclosed
WO-2016183359-A1 SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME BLINKBIO, INC. (US) 2016-11-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170202970-A1 SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME CD44, MSN, AS3MT TSHR 2393/4885
US-11497757-B2 Silanol based therapeutic payloads CD47, CD4, BST2 TSHR 3437/4885
US-11291731-B2 Silicon based drug conjugates and methods of using same CD44, MSN, AS3MT TSHR 2393/4885
US-20210161921-A1 Silanol Based Therapeutic Payloads CD47, CD4, BST2 TSHR 3437/4885
US-10716801-B2 Silanol based therapeutic payloads CD47, CD4, BST2 TSHR 3437/4885
US-20180200273-A1 Silanol Based Therapeutic Payloads CD47, CD4, BST2 TSHR 3437/4885
US-20230000993-A1 SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME CD44, MSN, AS3MT TSHR 2393/4885
US-20220184104-A1 SILANOL BASED THERAPEUTIC PAYLOADS CD47, CD4, BST2 TSHR 3437/4885
US-10064880-B2 Silanol based therapeutic payloads CD47, CD4, BST2 TSHR 3437/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.