Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18228368 | 0.90 | KLK7 (0.60) | KLK7RXFP1ALDH1A1HTTKDM4E | |
| SCHEMBL15646173 | 0.86 | KLK7 (0.58) | KLK7RXFP1ALDH1A1HTTKDM4E | |
| SCHEMBL21926498 | 0.84 | KLK7 (0.64) | KLK7RXFP1ALDH1A1HTTKDM4E | |
| SCHEMBL12049726 | 0.82 | KLK7 (0.56) | KLK7RXFP1ALDH1A1HTTKDM4E | |
| SCHEMBL16460192 | 0.81 | KLK7 (0.56) | KLK7RXFP1ALDH1A1HTTKDM4E | |
| SCHEMBL28187822 | 0.80 | ATM (0.57) | KLK7RXFP1ALDH1A1HTTKDM4E | |
| SCHEMBL12026432 | 0.79 | KDM2B (0.54) | KLK7RXFP1ALDH1A1HTTKDM4E | |
| SCHEMBL18228159 | 0.79 | CHRNB2 (0.49) | KLK7RXFP1ALDH1A1KDM4EMAPK1 | |
| SCHEMBL5046019 | 0.78 | SLC18A3 (0.54) | KLK7RXFP1ALDH1A1KDM4EMEN1 | |
| SCHEMBL9668119 | 0.78 | SLC18A3 (0.54) | KLK7RXFP1ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016180536-A1 | SUBSTITUTED QUINOXALINE DERIVATIVES | SELVITA S.A. (PL) | 2016-11-17 | — | — | WO | disclosed |