Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 1/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | VNN1 | O95497 | 1/20 | 0.52 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15646173 | 0.90 | KLK7 (0.58) | KLK7RXFP1ALDH1A1HTTKDM4E | |
| SCHEMBL21926836 | 0.89 | ALDH1A1 (0.57) | KLK7RXFP1ALDH1A1HTTKDM4E | |
| SCHEMBL21926987 | 0.88 | CYP1A2 (0.64) | KLK7RXFP1ALDH1A1KDM4ELMNA | |
| SCHEMBL7302157 | 0.87 | ALDH1A1 (0.62) | KLK7RXFP1ALDH1A1HTTKDM4E | |
| SCHEMBL5479680 | 0.87 | ALDH1A1 (0.62) | ALDH1A1LMNAPKMHSP90AA1MAPT | |
| SCHEMBL18228368 | 0.86 | KLK7 (0.60) | KLK7RXFP1ALDH1A1HTTKDM4E | |
| SCHEMBL18239387 | 0.84 | KLK7 (0.58) | KLK7RXFP1ALDH1A1HTTKDM4E | |
| SCHEMBL5908875 | 0.84 | VNN1 (0.67) | KLK7RXFP1ALDH1A1HTTKDM4E | |
| SCHEMBL12049726 | 0.83 | KLK7 (0.56) | KLK7RXFP1ALDH1A1HTTKDM4E | |
| SCHEMBL21926387 | 0.82 | CYP2D6 (0.60) | ALDH1A1HTTKDM4ELMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200131125-A1 | ARYL-PIPERIDINE DERIVATIVES | ARTAX BIOPHARMA INC. | 2020-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200131125-A1 | ARYL-PIPERIDINE DERIVATIVES | CD4, CD2, CCR1 | KLK7 3905/4885RXFP1 1426/4885ALDH1A1 1450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.