Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL27892275 | 1.00 | CYP2D6 (0.40) | CYP2D6 | |
| SCHEMBL107627 | 0.84 | NFKB1 (0.43) | CYP2D6 | |
| Ammonia Solution, Strong SCHEMBL9315030 | 0.81 | NFKB1 (0.40) | CYP2D6 | |
| SCHEMBL15333 | 0.80 | — | — | |
| SCHEMBL10425917 | 0.80 | FDPS (0.31) | CYP2D6 | |
| Ethylenediamine SCHEMBL27604806 | 0.78 | CYP2D6 (0.47) | CYP2D6 | |
| Ethylenediamine SCHEMBL7627681 | 0.78 | — | — | |
| Propane SCHEMBL27940504 | 0.76 | TSHR (0.39) | CYP2D6 | |
| SCHEMBL28598260 | 0.75 | CYP2D6 (0.77) | CYP2D6 | |
| Hydrochloric Acid SCHEMBL5586398 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014695-B1 | Aliphatic polyester polymer compositions and preparation method thereof | IND TECH RES INST (TW) | 2011-05-04 | — | — | EP | claimed |
| EP-2014695-A1 | Aliphatic polyester polymer compositions and preparation method thereof | Industrial Technology Research Institut (TW) | 2009-01-14 | — | — | EP | claimed |
| US-20070155943-A1 | Aliphatic polyester polymer compositions and preparation method thereof | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE | 2007-07-05 | — | — | US | claimed |
| EP-2014695-B1 | Aliphatic polyester polymer compositions and preparation method thereof | IND TECH RES INST (TW) | 2011-05-04 | — | — | EP | disclosed |
| EP-2014695-A1 | Aliphatic polyester polymer compositions and preparation method thereof | Industrial Technology Research Institut (TW) | 2009-01-14 | — | — | EP | disclosed |