SCHEMBL18242015

SCHEMBL18242015

C[CH]c1cccc(C(Cl)(Cl)C(Cl)(Cl)C(Cl)(Cl)C(Cl)(Cl)Cl)c1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 1/20 0.33
PGK1 P00558 1/20 0.32
PGK2 P07205 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18242513 0.95 NFE2L2 (0.34) NFE2L2PGK1PGK2
SCHEMBL18242756 0.87 NFE2L2 (0.36) NFE2L2PGK1PGK2
SCHEMBL18378492 0.83 NFE2L2 (0.32) NFE2L2PGK1PGK2
SCHEMBL18242217 0.81 NFE2L2 (0.31) NFE2L2
SCHEMBL18244036 0.80 NFE2L2 (0.30) NFE2L2
SCHEMBL18242450 0.79 TSHR (0.42) NFE2L2PGK1PGK2
SCHEMBL18242861 0.77 NFE2L2 (0.33) NFE2L2PGK1PGK2
SCHEMBL18242274 0.77
SCHEMBL18378489 0.76 NFE2L2 (0.32) NFE2L2PGK1PGK2
SCHEMBL18242909 0.75 NFE2L2 (0.31) NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10451967-B2 Acid- and radical-generating agent and method for generating acid and radical FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2019-10-22 US disclosed
US-20160342084-A1 ACID- AND RADICAL-GENERATING AGENT AND METHOD FOR GENERATING ACID AND RADICAL FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2016-11-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10451967-B2 Acid- and radical-generating agent and method for generating acid and radical CBR1, HAO2, CBR3 NFE2L2 45/4885PGK1 2952/4885PGK2 2580/4885
US-20160342084-A1 ACID- AND RADICAL-GENERATING AGENT AND METHOD FOR GENERATING ACID AND RADICAL CBR1, HAO2, CBR3 NFE2L2 45/4885PGK1 2952/4885PGK2 2580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.