SCHEMBL1824587

SCHEMBL1824587

[CH2]C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)F

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
TSHR P16473 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL503557 1.00 KDM4E (0.34) KDM4ETSHRTDP1
SCHEMBL5485467 1.00 KDM4E (0.34) KDM4ETSHRTDP1
SCHEMBL503323 1.00 KDM4E (0.34) KDM4ETSHRTDP1
SCHEMBL5489780 1.00 KDM4E (0.34) KDM4ETSHRTDP1
SCHEMBL5483220 1.00 KDM4E (0.34) KDM4ETSHRTDP1
SCHEMBL384855 1.00 KDM4E (0.34) KDM4ETSHRTDP1
SCHEMBL5490351 1.00 KDM4E (0.34) KDM4ETSHRTDP1
SCHEMBL503358 1.00 KDM4E (0.34) KDM4ETSHRTDP1
SCHEMBL444237 0.97 KDM4E (0.36) KDM4ETSHRTDP1
SCHEMBL145339 0.88 KDM4E (0.37) KDM4ETSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0887637-B1 Use of synthetic polymer particles as standards and calibrators in flow cytometry BAYER CORP (US) 2006-09-13 EP claimed
US-4933406-A OXYGEN-PERMEABLE, RIGID NIPPON OIL AND FATS CO., LTD. (JP) 1990-06-12 US claimed
US-11718810-B2 Lubricating oil composition and method for defoaming lubricating oil, and defoaming agent composition ENEOS CORPORATION (JP) 2023-08-08 US disclosed
US-20230159848-A1 DEFOAMING AGENT AND LUBRICATING OIL COMPOSITION ENEOS CORPORATION (JP) 2023-05-25 US disclosed
EP-4112150-A1 ANTIFOAMING AGENT, AND LUBRICATING OIL COMPOSITION ENEOS Corporation (JP) 2023-01-04 EP disclosed
US-20220204884-A1 LUBRICATING OIL COMPOSITION AND METHOD FOR DEFOAMING LUBRICATING OIL, AND DEFOAMING AGENT COMPOSITION ENEOS CORPORATION (JP) 2022-06-30 US disclosed
EP-3954452-A1 LUBRICATING OIL COMPOSITION AND LUBRICATING OIL DEFOAMING METHOD, AND DEFOAMING AGENT COMPOSITION ENEOS Corporation (JP) 2022-02-16 EP disclosed
EP-3733256-B1 USE OF A DEFOAMING AGENT, DEFOAMING AGENT AND LUBRICATING OIL COMPOSITION CONTAINING SAME JXTG NIPPON OIL & ENERGY CORP (JP) 2021-12-29 EP disclosed
EP-3339402-B1 LUBRICATING OIL COMPOSITION, DEFOAMING METHOD FOR LUBRICATING OIL, AND DEFOAMING AGENT COMPOSITION JXTG NIPPON OIL & ENERGY CORP (JP) 2021-08-18 EP disclosed
US-11046907-B2 Defoaming agent and lubricating oil composition ENEOS CORPORATION (JP) 2021-06-29 US disclosed
EP-3338871-B1 DEFOAMING AGENT AND LUBRICATING OIL COMPOSITION JXTG NIPPON OIL & ENERGY CORP (JP) 2021-04-14 EP disclosed
US-5770108-A HIGH SPEED RESPONSE, MOLECULAR ORIENTATION, HIGH CONTRAST, RECEPTIVITY MITSUI TOATSU CHEMICALS, INC. (JP) 1998-06-23 US disclosed
US-5708049-A Colored contact lens and method for producing the same SEIKO EPSON CORPORATION (JP) 1998-01-13 US disclosed
EP-0757032-A2 Naphthalene compound, and liquid crystal composition and liquid crystal element using the same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-02-05 EP disclosed
EP-0751133-A1 Pyrimidine compound, and liquid crystal composition and liquid crystal element using the same MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1997-01-02 EP disclosed
EP-0726474-A2 Colored contact lens and method for producing the same SEIKO EPSON CORPORATION (JP) 1996-08-14 EP disclosed
US-5190688-A Perfluoroalkyl Compounds Dopes MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1993-03-02 US disclosed
EP-0300009-B1 LIQUID CRYSTALLINE MIXTURE MERCK PATENT GmbH (DE) 1992-01-02 EP disclosed
US-4933406-A OXYGEN-PERMEABLE, RIGID NIPPON OIL AND FATS CO., LTD. (JP) 1990-06-12 US disclosed
US-4385110-A EMULSION CONTAINING A FLUOROALKYL SULFONATE OR SULFATE ANIONIC SURFACTANT FUJI PHOTO FILM CO., LTD. (JP) 1983-05-24 US disclosed