SCHEMBL444237

SCHEMBL444237

[CH2]C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)F

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
TSHR P16473 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5490351 0.97 KDM4E (0.34) KDM4ETSHRTDP1
SCHEMBL503323 0.97 KDM4E (0.34) KDM4ETSHRTDP1
SCHEMBL384855 0.97 KDM4E (0.34) KDM4ETSHRTDP1
SCHEMBL1824587 0.97 KDM4E (0.34) KDM4ETSHRTDP1
SCHEMBL5483220 0.97 KDM4E (0.34) KDM4ETSHRTDP1
SCHEMBL503557 0.97 KDM4E (0.34) KDM4ETSHRTDP1
SCHEMBL503358 0.97 KDM4E (0.34) KDM4ETSHRTDP1
SCHEMBL5485467 0.97 KDM4E (0.34) KDM4ETSHRTDP1
SCHEMBL5489780 0.97 KDM4E (0.34) KDM4ETSHRTDP1
SCHEMBL145339 0.90 KDM4E (0.37) KDM4ETSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6410612-B1 ACRYLIC POLYMER BLEND KURARAY CO., LTD. (JP) 2002-06-25 US claimed
US-11993578-B2 Pyrazole-3-carboxylic acid amide derivative and pest control agent KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2024-05-28 US disclosed
US-20240172550-A1 CHARGE-TRANSPORTING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2024-05-23 US disclosed
EP-4371979-A1 FORMAMIDE DERIVATIVE AND AGRICULTURAL OR HORTICULTURAL PLANT DISEASE CONTROL AGENT Kumiai Chemical Industry Co., Ltd. (JP) 2024-05-22 EP disclosed
US-11964957-B2 Pyrazole derivative and harmful organism-controlling agent KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2024-04-23 US disclosed
EP-3808738-B1 PYRAZOLE DERIVATIVE AND HARMFUL ORGANISM-CONTROLLING AGENT KUMIAI CHEMICAL INDUSTRY CO (JP) 2024-04-17 EP disclosed
WO-2024071060-A1 CHARGE-TRANSPORTING COMPOSITION 日産化学株式会社 2024-04-04 WO disclosed
US-11795270-B2 Triazine ring-containing polymer and film forming composition containing same NISSAN CHEMICAL CORPORATION (JP) 2023-10-24 US disclosed
WO-2023189399-A1 POLYMER AND USE THEREOF 日産化学株式会社 2023-10-05 WO disclosed
US-20230200203-A1 COMPOSITION FOR HOLE COLLECTING LAYER OF ORGANIC PHOTOELECTRIC CONVERSION ELEMENT NISSAN CHEMICAL CORPORATION (JP) 2023-06-22 US disclosed
US-5861108-A IMPROVES HIGH SPEED RESPONSE PROPERTY AND TEMPERATURE DEPENDENCY OF THE RESPONSE TIME MITSUI CHEMICALS, INC. (JP) 1999-01-19 US disclosed
US-5770108-A HIGH SPEED RESPONSE, MOLECULAR ORIENTATION, HIGH CONTRAST, RECEPTIVITY MITSUI TOATSU CHEMICALS, INC. (JP) 1998-06-23 US disclosed
EP-0757032-A2 Naphthalene compound, and liquid crystal composition and liquid crystal element using the same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-02-05 EP disclosed
EP-0751133-A1 Pyrimidine compound, and liquid crystal composition and liquid crystal element using the same MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1997-01-02 EP disclosed
EP-0248421-B1 Carrier for developer FUJI XEROX CO LTD (JP) 1994-09-07 EP disclosed
US-5110703-A Particles of magnetic powder in binder resin blend of polyolefin and olefin polymer having functional group FUJI XEROX CO., LTD. (JP) 1992-05-05 US disclosed
US-4965160-A CHARGE QUALITY FUJI XEROX CO., LTD. (JP) 1990-10-23 US disclosed
US-4954409-A FLUORINATED ACRYLIC POLYMER FUJI XEROX CO., LTD. (JP) 1990-09-04 US disclosed
US-4868083-A Developer carrier and process for producing the same FUJI XEROX CO., LTD. (JP) 1989-09-19 US disclosed
US-4791041-A FLUORINATED ALKYL (METH)ARYLATE COPOLYMER OVERCOATINGS; ANTISOILANTS; ANTISTICKING AGENTS FUJI XEROX CO., LTD. (JP) 1988-12-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11964957-B2 Pyrazole derivative and harmful organism-controlling agent L3MBTL3, L3MBTL1, L3MBTL4 KDM4E 1473/4885TSHR 870/4885TDP1 3190/4885
US-11993578-B2 Pyrazole-3-carboxylic acid amide derivative and pest control agent H1-3, HDAC3, H1-0 KDM4E 3999/4885TSHR 297/4885TDP1 3693/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.