Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9893131 | 0.76 | AR (0.43) | ALDH1A1 | |
| SCHEMBL28350279 | 0.73 | HTR2A (0.42) | SLC6A7KDM4E | |
| SCHEMBL13861157 | 0.65 | — | — | |
| SCHEMBL5487843 | 0.64 | MEN1 (0.45) | LMNAALDH1A1 | |
| SCHEMBL8983628 | 0.64 | SLC6A2 (0.49) | KDM4EALDH1A1 | |
| SCHEMBL1267349 | 0.61 | KDM4E (0.56) | LMNAKDM4EALDH1A1 | |
| SCHEMBL25247899 | 0.61 | SLC6A7 (0.42) | SLC6A7LMNAKDM4EALDH1A1 | |
| SCHEMBL5778408 | 0.61 | SLC6A7 (0.42) | SLC6A7LMNAKDM4EALDH1A1 | |
| SCHEMBL10243308 | 0.61 | KDM4E (0.51) | LMNAKDM4EALDH1A1 | |
| SCHEMBL27906828 | 0.60 | TRPV1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3298002-A1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2018-03-28 | — | — | EP | disclosed |
| WO-2016185423-A1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2016-11-24 | — | — | WO | disclosed |