Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.53 |
| ▸ | FAAH | O00519 | 4/20 | 0.53 |
| ▸ | CNR1 | P21554 | 2/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.50 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | F7 | P08709 | 3/20 | 0.47 |
| ▸ | F3 | P13726 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | FABP3 | P05413 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18248575 | 0.97 | FAAH (0.51) | EPHX2FAAHCNR1CNR2CSNK1E | |
| SCHEMBL11357056 | 0.97 | FAAH (0.51) | EPHX2FAAHCNR1CNR2CSNK1E | |
| SCHEMBL18248569 | 0.97 | FAAH (0.51) | EPHX2FAAHCNR1CNR2CSNK1E | |
| SCHEMBL18248593 | 0.94 | EPHX2 (0.52) | EPHX2FAAHCNR1CNR2KDM4E | |
| SCHEMBL18248541 | 0.93 | EPHX2 (0.53) | EPHX2FAAHCNR1CNR2KDM4E | |
| SCHEMBL31512495 | 0.90 | EPHX2 (0.55) | EPHX2FAAHCNR1CNR2KDM4E | |
| SCHEMBL28058533 | 0.89 | CSNK1E (0.57) | CSNK1E | |
| SCHEMBL22558568 | 0.89 | CSNK1E (0.57) | CSNK1E | |
| SCHEMBL28081007 | 0.89 | CSNK1E (0.57) | CSNK1E | |
| SCHEMBL7789683 | 0.89 | CSNK1E (0.57) | CSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110538170-B | Application of macamides compound or salt thereof in preparation of medicine for preventing or treating hepatic fibrosis diseases | 南华大学 | 2023-01-06 | — | — | CN | claimed |
| CN-110538170-A | Application of macamides compound or salt thereof in preparation of medicine for preventing or treating hepatic fibrosis diseases | UNIV SOUTH CHINA | 2019-12-06 | — | — | CN | claimed |
| CN-110538170-B | Application of macamides compound or salt thereof in preparation of medicine for preventing or treating hepatic fibrosis diseases | 南华大学 | 2023-01-06 | — | — | CN | disclosed |
| CN-106723001-B | Method for increasing content of amide in maca, prepared product and application of product | 中国科学院过程工程研究所 | 2021-01-22 | — | — | CN | disclosed |
| CN-110538170-A | Application of macamides compound or salt thereof in preparation of medicine for preventing or treating hepatic fibrosis diseases | UNIV SOUTH CHINA | 2019-12-06 | — | — | CN | disclosed |
| EP-3297621-A1 | A METHOD FOR TREATING PERIPHERAL INFLAMMATORY DISEASE | Dublin City University (IE) | 2018-03-28 | — | — | EP | disclosed |
| WO-2016185025-A1 | A METHOD FOR TREATING PERIPHERAL INFLAMMATORY DISEASE | DUBLIN CITY UNIVERSITY (IE) | 2016-11-24 | — | — | WO | disclosed |