Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.52 |
| ▸ | FAAH | O00519 | 4/20 | 0.51 |
| ▸ | CNR1 | P21554 | 2/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18248544 | 0.94 | EPHX2 (0.53) | EPHX2FAAHCNR1CNR2KDM4E | |
| SCHEMBL18248575 | 0.91 | FAAH (0.51) | EPHX2FAAHCNR1CNR2 | |
| SCHEMBL18248569 | 0.91 | FAAH (0.51) | EPHX2FAAHCNR1CNR2 | |
| SCHEMBL11357056 | 0.91 | FAAH (0.51) | EPHX2FAAHCNR1CNR2 | |
| SCHEMBL18248541 | 0.86 | EPHX2 (0.53) | EPHX2FAAHCNR1CNR2KDM4E | |
| SCHEMBL2187591 | 0.83 | CSNK1E (0.55) | CNR2 | |
| SCHEMBL31512495 | 0.83 | EPHX2 (0.55) | EPHX2FAAHCNR1CNR2KDM4E | |
| SCHEMBL22558568 | 0.82 | CSNK1E (0.57) | — | |
| SCHEMBL28058533 | 0.82 | CSNK1E (0.57) | — | |
| SCHEMBL28081007 | 0.82 | CSNK1E (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3297621-A1 | A METHOD FOR TREATING PERIPHERAL INFLAMMATORY DISEASE | Dublin City University (IE) | 2018-03-28 | — | — | EP | disclosed |
| WO-2016185025-A1 | A METHOD FOR TREATING PERIPHERAL INFLAMMATORY DISEASE | DUBLIN CITY UNIVERSITY (IE) | 2016-11-24 | — | — | WO | disclosed |