Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.65 |
| ▸ | CNR1 | P21554 | 5/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | F7 | P08709 | 3/20 | 0.56 |
| ▸ | F3 | P13726 | 3/20 | 0.56 |
| ▸ | PPARG | P37231 | 2/20 | 0.56 |
| ▸ | PPARD | Q03181 | 2/20 | 0.56 |
| ▸ | PPARA | Q07869 | 2/20 | 0.56 |
| ▸ | FABP3 | P05413 | 2/20 | 0.56 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.56 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28504984 | 1.00 | KDM4E (0.65) | KDM4ESOAT1CNR1CYP3A4MEN1 | |
| SCHEMBL29689655 | 1.00 | KDM4E (0.65) | KDM4ESOAT1CNR1CYP3A4MEN1 | |
| SCHEMBL9238140 | 0.97 | FAAH (0.59) | KDM4ESOAT1CNR1CYP3A4MEN1 | |
| SCHEMBL20303229 | 0.97 | FAAH (0.59) | KDM4ESOAT1CNR1CYP3A4MEN1 | |
| SCHEMBL10800485 | 0.97 | FAAH (0.59) | KDM4ESOAT1CNR1CYP3A4MEN1 | |
| SCHEMBL6283769 | 0.97 | FAAH (0.59) | KDM4ESOAT1CNR1CYP3A4MEN1 | |
| SCHEMBL379106 | 0.97 | FAAH (0.59) | KDM4ESOAT1CNR1CYP3A4MEN1 | |
| SCHEMBL17629191 | 0.87 | ALDH1A1 (0.60) | KDM4ESOAT1CYP3A4MEN1TP53 | |
| SCHEMBL1331618 | 0.87 | ALDH1A1 (0.60) | KDM4ESOAT1CYP3A4MEN1TP53 | |
| SCHEMBL28502905 | 0.87 | ALDH1A1 (0.60) | KDM4ESOAT1CYP3A4MEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3297621-A1 | A METHOD FOR TREATING PERIPHERAL INFLAMMATORY DISEASE | Dublin City University (IE) | 2018-03-28 | — | — | EP | disclosed |
| WO-2016185025-A1 | A METHOD FOR TREATING PERIPHERAL INFLAMMATORY DISEASE | DUBLIN CITY UNIVERSITY (IE) | 2016-11-24 | — | — | WO | disclosed |