Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18249432 | 0.87 | CYP4A11 (0.42) | CYP4F2CYP4A11PRKCAPRKCDMAPT | |
| SCHEMBL18249444 | 0.87 | UTS2R (0.46) | PRKCAPRKCDALDH1A1KMT2ATSHR | |
| SCHEMBL18249453 | 0.82 | POLB (0.43) | PRKCAPRKCDALDH1A1KMT2APOLB | |
| SCHEMBL18249448 | 0.81 | CYP4F2 (0.41) | CYP4F2CYP4A11MAPTNPC1RAB9A | |
| SCHEMBL17699419 | 0.79 | CYP4A11 (0.50) | CYP4F2CYP4A11PRKCAPRKCDMAPT | |
| SCHEMBL18249406 | 0.79 | TSHR (0.42) | CYP4F2CYP4A11MAPTNPC1RAB9A | |
| SCHEMBL15270059 | 0.79 | CYP4F2 (0.43) | CYP4F2CYP4A11PRKCAPRKCDMAPT | |
| SCHEMBL18249485 | 0.77 | GAA (0.47) | NPC1RAB9AALDH1A1KMT2APOLB | |
| SCHEMBL18249399 | 0.77 | MAPT (0.38) | CYP4F2CYP4A11MAPTNPC1RAB9A | |
| SCHEMBL20164227 | 0.76 | ALDH1A1 (0.49) | MAPTNPC1RAB9AALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3298048-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2018-03-28 | — | — | EP | disclosed |
| WO-2016184884-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2016-11-24 | — | — | WO | disclosed |