Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 7/20 | 0.46 |
| ▸ | SCN1A | P35498 | 3/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.45 |
| ▸ | MAOA | P21397 | 3/20 | 0.45 |
| ▸ | DRD3 | P35462 | 3/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | HRH2 | P25021 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20164216 | 0.92 | ALDH1A1 (0.52) | ALDH1A1MAPTPHLPP2LMNASCN1A | |
| SCHEMBL20164277 | 0.83 | LMNA (0.58) | ALDH1A1MAPTPHLPP2LMNASCN1A | |
| SCHEMBL571227 | 0.81 | CA1 (0.63) | ALDH1A1LMNACYP1A2MAOAKCNH2 | |
| SCHEMBL20164298 | 0.80 | LMNA (0.41) | ALDH1A1MAPTLMNASCN1ASCN2A | |
| SCHEMBL18249406 | 0.79 | TSHR (0.42) | ALDH1A1MAPTLMNADRD3SIGMAR1 | |
| SCHEMBL10949603 | 0.79 | ALDH1A1 (0.68) | ALDH1A1MAPTLMNACYP1A2MAPK1 | |
| SCHEMBL20164272 | 0.78 | MAPT (0.38) | ALDH1A1MAPTLMNACYP1A2MAOA | |
| SCHEMBL16555724 | 0.77 | TSHR (0.49) | ALDH1A1MAPTLMNASCN1ASCN2A | |
| SCHEMBL18249399 | 0.77 | MAPT (0.38) | ALDH1A1MAPTLMNACYP1A2MAOA | |
| SCHEMBL18249486 | 0.76 | ACHE (0.44) | ALDH1A1MAPTLMNACYP1A2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3298048-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2019-07-03 | — | — | EP | disclosed |
| US-10221256-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2019-03-05 | — | — | US | disclosed |
| US-20180142044-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-05-24 | — | — | US | disclosed |