Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.69 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | TYMP | P19971 | 3/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | DPP4 | P27487 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.63 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.63 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.63 |
| ▸ | GAPDH | P04406 | 1/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.63 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.63 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.63 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.63 |
| ▸ | STAT6 | P42226 | 1/20 | 0.63 |
| ▸ | PI4KA | P42356 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Inosine SCHEMBL13062153 | 1.00 | PAX8 (0.69) | PAX8P2RX3HPGDTYMPMAPK1 | |
| Inosine SCHEMBL13320592 | 1.00 | PAX8 (0.69) | PAX8P2RX3HPGDTYMPMAPK1 | |
| Inosine SCHEMBL6748953 | 1.00 | PAX8 (0.69) | PAX8P2RX3HPGDTYMPMAPK1 | |
| Inosine SCHEMBL12964365 | 1.00 | PAX8 (0.69) | PAX8P2RX3HPGDTYMPMAPK1 | |
| Inosine SCHEMBL1738548 | 1.00 | PAX8 (0.69) | PAX8P2RX3HPGDTYMPMAPK1 | |
| Inosine SCHEMBL16707275 | 1.00 | PAX8 (0.69) | PAX8P2RX3HPGDTYMPMAPK1 | |
| Inosine SCHEMBL13012212 | 1.00 | PAX8 (0.69) | PAX8P2RX3HPGDTYMPMAPK1 | |
| Inosine SCHEMBL6933022 | 1.00 | PAX8 (0.69) | PAX8P2RX3HPGDTYMPMAPK1 | |
| Inosine SCHEMBL10001664 | 1.00 | PAX8 (0.69) | PAX8P2RX3HPGDTYMPMAPK1 | |
| Inosine SCHEMBL29669658 | 1.00 | PAX8 (0.69) | PAX8P2RX3HPGDTYMPMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10882903-B2 | Methods and compositions for treating an alphavirus infection | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2021-01-05 | — | — | US | disclosed |
| US-20180134778-A1 | METHODS AND COMPOSITIONS FOR TREATING AN ALPHAVIRUS INFECTION | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2018-05-17 | — | — | US | disclosed |
| WO-2016187312-A1 | METHODS AND COMPOSITIONS FOR TREATING AN ALPHAVIRUS INFECTION | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2016-11-24 | — | — | WO | disclosed |