Sugi Predict

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Inosine

Inosine

SCHEMBL1738548

O=c1[nH]cnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PAX8 Q06710 1/20 0.69
▸ P2RX3 P56373 1/20 0.69
▸ HPGD P15428 1/20 0.67
▸ TYMP P19971 3/20 0.65
▸ MAPK1 P28482 2/20 0.63
▸ DPP4 P27487 1/20 0.63
▸ MEN1 O00255 1/20 0.63
▸ SLC28A1 O00337 1/20 0.63
▸ MAP3K7 O43318 1/20 0.63
▸ SLC28A2 O43868 1/20 0.63
▸ GAPDH P04406 1/20 0.63
▸ ADORA3 P0DMS8 1/20 0.63
▸ ADORA2A P29274 1/20 0.63
▸ ADORA2B P29275 1/20 0.63
▸ ADORA1 P30542 1/20 0.63
▸ STAT6 P42226 1/20 0.63
▸ PI4KA P42356 1/20 0.63
▸ KMT2A Q03164 1/20 0.63
▸ SMN1; SMN2 Q16637 1/20 0.63
▸ PI4K2B Q8TCG2 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Inosine SCHEMBL13062153 1.00 PAX8 (0.69) PAX8P2RX3HPGDTYMPMAPK1
Inosine SCHEMBL13320592 1.00 PAX8 (0.69) PAX8P2RX3HPGDTYMPMAPK1
Inosine SCHEMBL6748953 1.00 PAX8 (0.69) PAX8P2RX3HPGDTYMPMAPK1
Inosine SCHEMBL18249508 1.00 PAX8 (0.69) PAX8P2RX3HPGDTYMPMAPK1
Inosine SCHEMBL12964365 1.00 PAX8 (0.69) PAX8P2RX3HPGDTYMPMAPK1
Inosine SCHEMBL16707275 1.00 PAX8 (0.69) PAX8P2RX3HPGDTYMPMAPK1
Inosine SCHEMBL13012212 1.00 PAX8 (0.69) PAX8P2RX3HPGDTYMPMAPK1
Inosine SCHEMBL6933022 1.00 PAX8 (0.69) PAX8P2RX3HPGDTYMPMAPK1
Inosine SCHEMBL10001664 1.00 PAX8 (0.69) PAX8P2RX3HPGDTYMPMAPK1
Inosine SCHEMBL29669658 1.00 PAX8 (0.69) PAX8P2RX3HPGDTYMPMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11021497-B2 Compositions and methods for synthesis of phosphorylated molecules THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-06-01 — — US claimed
US-20200239500-A1 Compositions and Methods for Synthesis of Phosphorylated Molecules THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2020-07-30 — — US claimed
US-7807653-B2 Nucleotide mimics and their prodrugs BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2010-10-05 — — US claimed
US-20070265224-A1 Nucleotide mimics and their prodrugs BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2007-11-15 — — US claimed
EP-1539188-A2 NUCLEOSIDE DERIVATIVES AS INHIBITORS OF RNA-DEPENDENT RNA VIRAL POLYMERASE Merck & Co., Inc. (US) 2005-06-15 — — EP claimed
EP-1485395-A2 NUCLEOTIDE MIMICS AND THEIR PRODRUGS Biota, Inc. (US) 2004-12-15 — — EP claimed
WO-2003072757-A9 NUCLEOTIDE MIMICS AND THEIR PRODRUGS BIOTA INC (US) 2004-10-21 — — WO claimed
US-20040110717-A1 Nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase MERCK SHARP & DOHME LLC 2004-06-10 — — US claimed
US-20040059104-A1 Nucleotide mimics and their prodrugs BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2004-03-25 — — US claimed
WO-2003072757-A2 NUCLEOTIDE MIMICS AND THEIR PRODRUGS BIOTA, INC. (US) 2003-09-04 — — WO claimed
WO-2002057425-A2 NUCLEOSIDE DERIVATIVES AS INHIBITORS OF RNA-DEPENDENT RNA VIRAL POLYMERASE MERCK & CO., INC. (US) 2002-07-25 — — WO claimed
JP-55029941-A — — None — — JP disclosed
JP-55104894-A — — None — — JP disclosed
WO-2026090505-A1 FLUOROPYRIMIDINE PARTICLES FOR THE TREATMENT OF CANCER WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) 2026-04-30 — — WO disclosed
EP-4727562-A1 USE OF CD200AR-L FOR ENHANCING ADOPTIVE T-CELL THERAPY Elias Animal Health (US) 2026-04-22 — — EP disclosed
JP-S5529941-A PREPARATION OF PYRIMIDINE ARABINOSIDES AJINOMOTO CO INC 1980-03-03 — — JP disclosed
US-4188378-A Anticancer and antiviral activity of 9-β-D-arabinofuranosyl-2-fluoroadenine THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) 1980-02-12 — — US disclosed
US-4138562-A ANTITUMOR AGENTS, VIRICIDES THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1979-02-06 — — US disclosed
US-4093714-A VIRICIDES ICN PHARMACEUTICALS, INC. (US) 1978-06-06 — — US disclosed
JP-S05529941-A — — 0001-01-01 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070265224-A1 Nucleotide mimics and their prodrugs NUDT14, ENTPD5, MTAP PAX8 4415/4885P2RX3 119/4885HPGD 1161/4885
US-20200239500-A1 Compositions and Methods for Synthesis of Phosphorylated Molecules PIK3CA, CHAMP1, TYMP PAX8 4179/4885P2RX3 557/4885HPGD 2801/4885
US-20040110717-A1 Nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase NSUN2, NSUN3, POLRMT PAX8 4793/4885P2RX3 1502/4885HPGD 2317/4885
US-11021497-B2 Compositions and methods for synthesis of phosphorylated molecules PIK3CA, CHAMP1, TYMP PAX8 4179/4885P2RX3 557/4885HPGD 2801/4885
US-20040059104-A1 Nucleotide mimics and their prodrugs NUDT14, ENTPD5, MTAP PAX8 4415/4885P2RX3 119/4885HPGD 1161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.