Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.44 |
| ▸ | PHGDH | O43175 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709151 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2L3MBTL3L3MBTL1HRH3PHGDH | |
| SCHEMBL35550 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2L3MBTL3L3MBTL1HRH3PHGDH | |
| SCHEMBL1827648 | 0.97 | SMN1; SMN2 (0.54) | SMN1; SMN2L3MBTL3L3MBTL1HRH3PHGDH | |
| Methylamine SCHEMBL28019730 | 0.93 | SMN1; SMN2 (0.47) | SMN1; SMN2L3MBTL3L3MBTL1HRH3PHGDH | |
| SCHEMBL9425142 | 0.92 | SMN1; SMN2 (0.54) | SMN1; SMN2L3MBTL3L3MBTL1HRH3KDM4E | |
| SCHEMBL25672747 | 0.91 | L3MBTL3 (0.47) | SMN1; SMN2L3MBTL3L3MBTL1HRH3KDM4E | |
| SCHEMBL26025479 | 0.90 | SMN1; SMN2 (0.48) | SMN1; SMN2L3MBTL3L3MBTL1HRH3KDM4E | |
| SCHEMBL14907095 | 0.88 | L3MBTL3 (0.49) | SMN1; SMN2L3MBTL3L3MBTL1HRH3KDM4E | |
| SCHEMBL3168997 | 0.86 | — | — | |
| SCHEMBL26112782 | 0.86 | SMN1; SMN2 (0.52) | SMN1; SMN2L3MBTL3L3MBTL1HRH3MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118930764-A | Photo-moisture curable urethane compound, photo-moisture curable urethane prepolymer, and photo-moisture curable resin composition | 积水化学工业株式会社 | 2024-11-12 | — | — | CN | disclosed |
| CN-118930765-A | Photo-moisture curable urethane compound, photo-moisture curable urethane prepolymer, and photo-moisture curable resin composition | 积水化学工业株式会社 | 2024-11-12 | — | — | CN | disclosed |
| CN-113242869-B | Photo-moisture curable urethane compound, photo-moisture curable urethane prepolymer, and photo-moisture curable resin composition | 积水化学工业株式会社 | 2024-09-10 | — | — | CN | disclosed |
| CN-113242869-A | Light-moisture-curable urethane compound, light-moisture-curable urethane prepolymer, and light-moisture-curable resin composition | 积水化学工业株式会社 | 2021-08-10 | — | — | CN | disclosed |
| WO-2020129994-A1 | LIGHT/MOISTURE-CURABLE URETHANE-BASED COMPOUND, LIGHT/MOISTURE-CURABLE URETHANE POLYMER, AND LIGHT/MOISTURE-CURABLE RESIN COMPOSITION | 積水化学工業株式会社 | 2020-06-25 | — | — | WO | disclosed |
| US-20110183974-A1 | 1,2,4-OXADIAZOLE SUBSTITUTED PIPERIDINE AND PIPERAZINE DERIVATIVES AS SMO ANTAGONISTS | INSTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI (IT) | 2011-07-28 | — | — | US | disclosed |
| EP-2318400-A1 | 1,2,4-OXADIAZOLE SUBSTITUTED PIPERIDINE AND PIPERAZINE DERIVATIVES AS SMO ANTAGONISTS | Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. (IT) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010013037-A1 | 1,2,4-OXADIAZOLE SUBSTITUTED PIPERIDINE AND PIPERAZINE DERIVATIVES AS SMO ANTAGONISTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2010-02-04 | — | — | WO | disclosed |
| US-20090054448-A1 | Amino Acid Derivatives as Histone Deacetylase (HDAC) Inhibitors | JONES PHILIP | 2009-02-26 | — | — | US | disclosed |
| US-20080221157-A1 | Amide Derivatives as Inhibitors of Histone Deacetylase | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGE (IT) | 2008-09-11 | — | — | US | disclosed |
| EP-1945609-A2 | AMINO ACID DERIVATIVES AS HISTONE DEACETYLASE (HDAC) INHIBITORS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2008-07-23 | — | — | EP | disclosed |
| EP-1768955-A1 | AMIDE DERIVATIVES AS INHIBITORS OF HISTONE DEACETYLASE | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2007-04-04 | — | — | EP | disclosed |
| WO-2007029036-A2 | AMINO ACID DERIVATIVES AS HISTONE DEACETYLASE (HDAC) INHIBITORS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2007-03-15 | — | — | WO | disclosed |
| WO-2006005941-A1 | AMIDE DERIVATIVES AS INHIBITORS OF HISTONE DEACETYLASE | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI S.P.A. (IT) | 2006-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221157-A1 | Amide Derivatives as Inhibitors of Histone Deacetylase | HDAC1, HDAC5, HDAC4 | SMN1; SMN2 1329/4885L3MBTL3 2394/4885L3MBTL1 2041/4885 |
| US-20090054448-A1 | Amino Acid Derivatives as Histone Deacetylase (HDAC) Inhibitors | HDAC5, HDAC1, HDAC11 | SMN1; SMN2 1280/4885L3MBTL3 3832/4885L3MBTL1 3032/4885 |
| US-20110183974-A1 | 1,2,4-OXADIAZOLE SUBSTITUTED PIPERIDINE AND PIPERAZINE DERIVATIVES AS SMO ANTAGONISTS | SHH, SMO, GLI1 | SMN1; SMN2 518/4885L3MBTL3 4269/4885L3MBTL1 3642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.