Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | KDM4A | O75164 | 1/20 | 0.63 |
| ▸ | P2RX7 | Q99572 | 12/20 | 0.61 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | BCL2 | P10415 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1823184 | 1.00 | KDM4E (0.63) | KDM4EKDM4AP2RX7ITGB3ITGA2B | |
| SCHEMBL3580946 | 0.92 | P2RX7 (0.61) | KDM4EKDM4AP2RX7ABCB1BCL2 | |
| SCHEMBL3580949 | 0.92 | P2RX7 (0.61) | KDM4EKDM4AP2RX7ABCB1BCL2 | |
| SCHEMBL1827897 | 0.91 | P2RX7 (0.60) | KDM4EKDM4AP2RX7ABCB1BCL2 | |
| SCHEMBL1827899 | 0.91 | P2RX7 (0.60) | KDM4EKDM4AP2RX7ABCB1BCL2 | |
| SCHEMBL1823041 | 0.90 | P2RX7 (0.59) | KDM4EKDM4AP2RX7ABCB1BCL2 | |
| SCHEMBL1823039 | 0.90 | P2RX7 (0.59) | KDM4EKDM4AP2RX7ABCB1BCL2 | |
| SCHEMBL1825550 | 0.88 | P2RX7 (0.57) | KDM4EKDM4AP2RX7ABCB1BCL2 | |
| SCHEMBL1825549 | 0.88 | P2RX7 (0.57) | KDM4EKDM4AP2RX7ABCB1BCL2 | |
| SCHEMBL1827256 | 0.87 | P2RX7 (0.71) | KDM4EKDM4AP2RX7BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2161254-B1 | Intermediate for preparing a biaryl compound | SUMITOMO CHEMICAL CO (JP) | 2014-08-13 | — | — | EP | disclosed |
| EP-1481967-B1 | PROCESS FOR THE PREPARATION OF BIARYL COMPOUNDS | SUMITOMO CHEMICAL CO (JP) | 2011-05-04 | — | — | EP | disclosed |
| EP-2161254-A1 | Intermediate for preparing a biaryl compound | Sumitomo Chemical Company, Limited (JP) | 2010-03-10 | — | — | EP | disclosed |