Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 16/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | KDM4A | O75164 | 1/20 | 0.53 |
| ▸ | BCL2 | P10415 | 2/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3580946 | 1.00 | P2RX7 (0.61) | P2RX7KDM4EKDM4ABCL2ABCB1 | |
| SCHEMBL1827897 | 0.95 | P2RX7 (0.60) | P2RX7KDM4EKDM4ABCL2ABCB1 | |
| SCHEMBL1827899 | 0.95 | P2RX7 (0.60) | P2RX7KDM4EKDM4ABCL2ABCB1 | |
| SCHEMBL1823039 | 0.94 | P2RX7 (0.59) | P2RX7KDM4EKDM4ABCL2ABCB1 | |
| SCHEMBL1823041 | 0.94 | P2RX7 (0.59) | P2RX7KDM4EKDM4ABCL2ABCB1 | |
| SCHEMBL1825550 | 0.92 | P2RX7 (0.57) | P2RX7KDM4EKDM4ABCL2ABCB1 | |
| SCHEMBL1825549 | 0.92 | P2RX7 (0.57) | P2RX7KDM4EKDM4ABCL2ABCB1 | |
| SCHEMBL1824972 | 0.92 | KDM4E (0.63) | P2RX7KDM4EKDM4ABCL2ABCB1 | |
| SCHEMBL1823184 | 0.92 | KDM4E (0.63) | P2RX7KDM4EKDM4ABCL2ABCB1 | |
| SCHEMBL1828014 | 0.92 | P2RX7 (0.56) | P2RX7KDM4EKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7714157-B2 | Process for preparing a biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-05-11 | — | — | US | disclosed |
| US-20070270603-A1 | Process for preparing a biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED | 2007-11-22 | — | — | US | disclosed |
| US-7271280-B2 | Process for preparing a biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-09-18 | — | — | US | disclosed |
| EP-1481967-A1 | PROCESS FOR THE PREPARATION OF BIARYL COMPOUNDS | Sumitomo Chemical Company, Limited (JP) | 2004-12-01 | — | — | EP | disclosed |
| US-20040158093-A1 | Process for preparing a biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040158093-A1 | Process for preparing a biaryl compound | CYP1B1, REL, CYP2F1 | P2RX7 3606/4885KDM4E 2554/4885KDM4A 1127/4885 |
| US-20070270603-A1 | Process for preparing a biaryl compound | CYP4A11, CYP4B1, CYP51A1 | P2RX7 2747/4885KDM4E 2704/4885KDM4A 1554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.