Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 7/20 | 0.54 |
| ▸ | PDE4A | P27815 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 5/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17176249 | 0.81 | HTR3A (0.60) | HTR3ACNR2ATMCNR1 | |
| SCHEMBL19068184 | 0.78 | HTR3A (0.57) | HTR3ACNR2ATMCNR1 | |
| SCHEMBL17170603 | 0.77 | HTR3A (0.59) | HTR3ACNR2ATMCNR1 | |
| SCHEMBL7169759 | 0.74 | PDE4A (0.62) | PDE4AKCNH2 | |
| SCHEMBL9685522 | 0.74 | LMNA (0.64) | PDE4AKCNH2CNR2CNR1 | |
| SCHEMBL17176644 | 0.73 | HTR3A (0.59) | HTR3ACNR2ATMCNR1 | |
| SCHEMBL12496362 | 0.73 | PDE4A (0.54) | PDE4AKCNH2CNR2ATMCNR1 | |
| SCHEMBL17163701 | 0.72 | HTR3A (0.86) | HTR3A | |
| SCHEMBL17163703 | 0.72 | HTR3A (0.86) | HTR3A | |
| SCHEMBL17324756 | 0.71 | HTR3A (0.49) | HTR3ACNR2ATMCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011527320-A | — | — | 2011-10-27 | — | — | JP | claimed |
| EP-2315767-A2 | PYRIDINO-PYRIDINONE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2011-05-04 | — | — | EP | claimed |
| WO-2010004197-A2 | PYRIDINO-PYRIDINONE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2010-01-14 | — | — | WO | claimed |
| EP-2315767-A2 | PYRIDINO-PYRIDINONE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2011-05-04 | — | — | EP | disclosed |
| WO-2010004197-A2 | PYRIDINO-PYRIDINONE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2010-01-14 | — | — | WO | disclosed |