Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 5/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.53 |
| ▸ | MTOR | P42345 | 5/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.53 |
| ▸ | ABL1 | P00519 | 4/20 | 0.53 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.53 |
| ▸ | FYN | P06241 | 6/20 | 0.44 |
| ▸ | SRC | P12931 | 4/20 | 0.44 |
| ▸ | KDR | P35968 | 3/20 | 0.44 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.44 |
| ▸ | CDK1 | P06493 | 2/20 | 0.44 |
| ▸ | ROS1 | P08922 | 2/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.44 |
| ▸ | CDK2 | P24941 | 2/20 | 0.44 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.44 |
| ▸ | CLK2 | P49760 | 2/20 | 0.44 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30877161 | 0.86 | MTOR (0.54) | PIK3CGPIK3CDMTORPIK3CAABL1 | |
| SCHEMBL18250077 | 0.86 | MTOR (0.54) | PIK3CGPIK3CDMTORPIK3CAABL1 | |
| SCHEMBL17962785 | 0.84 | FYN (0.49) | PIK3CGPIK3CDMTORPIK3CAABL1 | |
| SCHEMBL20533626 | 0.82 | ADORA2A (0.49) | PIK3CGPIK3CDMTORPIK3CAABL1 | |
| SCHEMBL17936088 | 0.81 | MAPK1 (0.47) | PIK3CGPIK3CDMTORPIK3CAABL1 | |
| SCHEMBL19500708 | 0.80 | SRC (0.56) | PIK3CGPIK3CDMTORPIK3CAABL1 | |
| SCHEMBL19500707 | 0.80 | SRC (0.56) | PIK3CGPIK3CDMTORPIK3CAABL1 | |
| SCHEMBL868744 | 0.79 | PIK3CD (0.51) | PIK3CGPIK3CDMTORPIK3CAABL1 | |
| SCHEMBL24096870 | 0.79 | SRC (0.45) | PIK3CGPIK3CDMTORPIK3CAABL1 | |
| SCHEMBL17714345 | 0.77 | FYN (0.72) | PIK3CGPIK3CDPIK3CAABL1PIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107849050-B | Compound (I) | 爱丁堡大学董事会 | 2020-10-13 | — | — | CN | disclosed |
| EP-3298015-A1 | COMPOUNDS | The University Court of the University of Edinburgh (GB) | 2018-03-28 | — | — | EP | disclosed |
| WO-2016185160-A1 | COMPOUNDS | THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) | 2016-11-24 | — | — | WO | disclosed |